Randomized controlled trial2017

Dietary Nitrate Fails to Improve 1 and 4 km Cycling Performance in Highly Trained Cyclists

McQuillan JA, Dulson DK, Laursen PB, Kilding AE

International journal of sport nutrition and exercise metabolism · 23 citations

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Not stated

Who paid for it

Funding
Independent funding
University or hospital
Johns Hopkins University

Based on 1 listed funder(s).

Publication

Published
2016-12-20 · Int J Sport Nutr Exerc Metab · vol. 27 · issue 3 · pp. 255–263
Publisher
Human Kinetics
Cited
30 citations · more than 98% of similar papers · 10.7× the field average
Impact
Top 10% most cited in its field
References
0 works
Access
Paywalled
Research areas
Cardiovascular and exercise physiology · Pharmacological Effects and Assays · Muscle metabolism and nutrition
Keywords
Time trial, Placebo, Cycling, Crossover study, Dosing, Medicine, Animal science, Physical therapy, Internal medicine, Biology, Blood pressure, Heart rate
MeSH
humans, beta vulgaris, nitrates, nitric oxide, cross-over studies, double-blind method, oxygen consumption, bicycling, dietary supplements, adult, male, athletic performance, young adult, athletes, sports nutritional physiological phenomena, fruit and vegetable juices

4 authors

  • Joseph A. McQuillan
  • Deborah K. Dulson
  • Paul B. Laursen
  • Andrew Edward Kilding

Abstract

We aimed to compare the effects of two different dosing durations of dietary nitrate (NO3-) supplementation on 1 and 4 km cycling time-trial performance in highly trained cyclists. In a double-blind crossover-design, nine highly trained cyclists ingested 140ml of NO3- -rich beetroot juice containing ~8.0mmol [NO3-], or placebo, for seven days. Participants completed a range of laboratory-based trials to quantify physiological and perceptual responses and cycling performance: time-trials on day 3 and 6 (4km) and on day 4 and 7 (1km) of the supplementation period. Relative to placebo, effects following 3- and 4-days of NO3- supplementation were unclear for 4 (-0.8; 95% CL, ± 2.8%, p = .54) and likely harmful for 1km (-1.9; ± 2.5% CL, p = .17) time-trial mean power. Effects following 6- and 7-days of NO3- supplementation resulted in unclear effects for 4 (0.1; ± 2.2% CL, p = .93) and 1km (-0.9; ± 2.6%CL, p = .51) time-trial mean power. Relative to placebo, effects for 40, 50, and 60% peak power output were unclear for economy at days 3 and 6 of NO3- supplementation (p > .05). Dietary NO3- supplementation appears to be detrimental to 1km time-trial performance in highly trained cyclists after 4-days. While, extending NO3- dosing to ≥ 6-days reduced the magnitude of harm in both distances, overall performance in short duration cycling time-trials did not improve relative to placebo.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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