Feasibility of long-term continuous subcutaneous magnesium supplementation in a patient with irreversible magnesium wasting due to cisplatin
Vermeulen EA, Vervloet MG, Lubach CH, Nurmohamed SA, Penne EL
The Netherlands journal of medicine · 4 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Case report (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2017-01-01 · Neth J Med · vol. 75 · issue 1 · pp. 35–38
- Publisher
- National Institutes of Health
- Cited
- 6 citations · more than 67% of similar papers · 0.5× the field average
- References
- 0 works
- Access
- Paywalled
- Research areas
- Magnesium in Health and Disease · Chemotherapy-induced organ toxicity mitigation
- Keywords
- Medicine, Magnesium, Wasting, Magnesium deficiency (plants), Hypomagnesemia, Surgery, Anesthesia, Internal medicine
- MeSH
- humans, renal tubular transport, inborn errors, cisplatin, magnesium, treatment outcome, feasibility studies, time factors, dietary supplements, adult, female, infusions, subcutaneous
5 authors
From NL, US
- Emma A. VermeulenAmsterdam UMC Location Vrije Universiteit Amsterdam
- Marc G. Vervloet
- C. H. C. LubachAmsterdam UMC Location Vrije Universiteit Amsterdam
- Shaikh A. Nurmohamed
- Erik Lars PennePacific Clinics
Abstract
A 39-year-old woman presented with severe, uncontrolled and irreversible hypomagnesaemia, following cisplatin treatment in her childhood. Because high-dose oral magnesium supplementation therapy was insufficient and not tolerated, continuous subcutaneous magnesium supplementation was successfully instituted and continued in the outpatient setting. This case demonstrates that continuous subcutaneous magnesium supplementation is effective in maintaining magnesium levels within the normal range, is well tolerated and may provide a long-term solution for chronic hypomagnesaemia due to intractable renal losses.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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