Study2017Industry fundedOpen access

Funded in part by Danone

Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults

Perrier ET, Bottin JH, Vecchio M, Lemetais G

European journal of clinical nutrition · 42 citations

Review labels

Author industry tiesIndustry funded

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cross-sectional study (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Industry funded
Company
Danone
Authors
At least one author declares a financial tie to industry

Based on 1 listed funder(s) and full-text disclosure statement.

Publication

Published
2017-02-01 · Eur J Clin Nutr · vol. 71 · issue 4 · pp. 561–563
Publisher
Springer Nature
Cited
70 citations · more than 92% of similar papers · 3.3× the field average
Impact
Top 10% most cited in its field
References
13 works
Access
Open access (hybrid journal) · CC-BY-NC-ND
Research areas
Thermoregulation and physiological responses · Diet and metabolism studies · Sodium Intake and Health
Keywords
Urine specific gravity, Urine osmolality, Urine, Receiver operating characteristic, Medicine, Osmole, Urology, Area under the curve, Endocrinology, Internal medicine
MeSH
urine, humans, urinalysis, sensitivity and specificity, roc curve, drinking, specific gravity, color, reference values, adult, female, male, young adult, healthy volunteers, organism hydration status

4 authors

From FR

  • Erica T. Perrier · correspondingDanone (France)
  • Jeanne H. BottinDanone (France)
  • Marissa L. Del VecchioDanone (France)
  • Guillaume LemetaisDanone (France)

Abstract

Growing evidence suggests a distinction between water intake necessary for maintaining a euhydrated state, and water intake considered to be adequate from a perspective of long-term health. Previously, we have proposed that maintaining a 24-h urine osmolality (UOsm) of ⩽500 mOsm/kg is a desirable target for urine concentration to ensure sufficient urinary output to reduce renal health risk and circulating vasopressin. In clinical practice and field monitoring, the measurement of UOsm is not practical. In this analysis, we calculate criterion values for urine-specific gravity (USG) and urine color (UCol), two measures which have broad applicability in clinical and field settings. A receiver operating characteristic curve analysis performed on 817 urine samples demonstrates that a USG ⩾1.013 detects UOsm>500 mOsm/kg with very high accuracy (AUC 0.984), whereas a subject-assessed UCol⩾4 offers high sensitivity and moderate specificity (AUC 0.831) for detecting UOsm >500 m Osm/kg.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).

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