Effects of Acute Blueberry Flavonoids on Mood in Children and Young Adults
Khalid S, Barfoot KL, May G, Lamport DJ, Reynolds SA, Williams CM
Nutrients · 63 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food provided by researchers
Who paid for it
- Funding
- Independent funding
- Government
- Economic and Social Research Council
- Grants
- Economic and Social Research Council (1638818)
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2017-02-20 · Nutrients · vol. 9 · issue 2 · p. 158
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 92 citations · more than 99% of similar papers · 11.6× the field average
- Impact
- Top 10% most cited in its field
- References
- 48 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Medicinal Plant Extracts Effects · Medicinal Plants and Neuroprotection · Olfactory and Sensory Function Studies
- Keywords
- Mood, Affect (linguistics), Placebo, Cognition, Psychology, Clinical psychology, Flavonoid, Medicine, Psychological intervention, Randomized controlled trial, Rumination, Psychiatry, Internal medicine, Biology
- MeSH
- humans, fruit, flavonoids, cross-over studies, double-blind method, affect, adolescent, adult, child, female, male, young adult, executive function, blueberry plants
6 authors
From GB
- Sundus KhalidUniversity of Reading
- Katie L. BarfootUniversity of Reading
- Gabrielle MayUniversity of Reading
- Daniel Joseph LamportUniversity of Reading
- Shirley A. ReynoldsUniversity of Reading
- Claire Michelle Williams · correspondingUniversity of Reading
Abstract
Epidemiological evidence suggests that consumption of flavonoids (usually via fruits and vegetables) is associated with decreased risk of developing depression. One plausible explanation for this association is the well-documented beneficial effects of flavonoids on executive function (EF). Impaired EF is linked to cognitive processes (e.g., rumination) that maintain depression and low mood; therefore, improved EF may reduce depressionogenic cognitive processes and improve mood. Study 1: 21 young adults (18-21 years old) consumed a flavonoid-rich blueberry drink and a matched placebo in a counterbalanced cross-over design. Study 2: 50 children (7-10 years old) were randomly assigned to a flavonoid-rich blueberry drink or a matched placebo. In both studies, participants and researchers were blind to the experimental condition, and mood was assessed using the Positive and Negative Affect Schedule before and 2 h after consumption of the drinks. In both studies, the blueberry intervention increased positive affect (significant drink by session interaction) but had no effect on negative affect. This observed effect of flavonoids on positive affect in two independent samples is of potential practical value in improving public health. If the effect of flavonoids on positive affect is replicated, further investigation will be needed to identify the mechanisms that link flavonoid interventions with improved positive mood.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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