Randomized controlled trial2017

Novel Approach to Treating Androgenetic Alopecia in Females With Photobiomodulation (Low-Level Laser Therapy)

Friedman S, Schnoor P

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 33 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2017-03-23 · Dermatol Surg · vol. 43 · issue 6 · pp. 856–867
Publisher
Lippincott Williams & Wilkins
Cited
52 citations · more than 97% of similar papers · 6.1× the field average
Impact
Top 10% most cited in its field
References
42 works
Access
Paywalled
Research areas
Hair Growth and Disorders · Dermatologic Treatments and Research · Laser Applications in Dentistry and Medicine
Keywords
Scalp, Medicine, Laser therapy, Alopecia areata, Low level laser therapy, Dermatology, Randomized controlled trial, Hair follicle, Laser treatment, Laser, Surgery, Internal medicine
MeSH
humans, alopecia, double-blind method, adolescent, adult, middle aged, female, young adult, low-level light therapy

2 authors

From US

  • Shelly A. Friedman · correspondingScottsdale Research Institute (United States)
  • Patricia Schnoor

Abstract

Background

Photobiomodulation, also referred to as low-level laser therapy (LLLT), has been studied and used for (among other diseases) the promotion of hair regrowth.

Objective/materials and methods/results

A clinical study was developed to define the physiologic effects that occur when the human hair follicle and surrounding tissue structures are exposed to laser light using a novel device that is fitted with an array of laser diode sources operating at 650 nm and placed inside a sports cap to promote discretion while in use. The study demonstrates that low-level laser treatment of the scalp every other day for 17 weeks using the HANDI-DOME LASER device is a safe and effective treatment for androgenetic alopecia in healthy females between the ages of 18 to 60 with Fitzpatrick skin Types I to IV and Ludwig-Savin Baldness Scale I-2 to II-2 baldness patterns. Subjects receiving LLLT at 650 nm achieved a 51% increase in hair counts as compared with sham-treated control patients in this multicenter randomized controlled trial.

Conclusion

These results suggest that the emerging technology of low-level laser therapy may play a potentially significant role in health care providers' armamentarium for the disease androgenic alopecia.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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