Red meat consumption and cardiovascular target organ damage (from the Strong Heart Study)
Haring B, Wang W, Fretts A, Shimbo D, Lee ET, Howard BV, Roman MJ, Devereux RB
Journal of hypertension · 9 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- Nonprofit
- Wellcome Trust
- Government
- Scottish Government
- University or hospital
- Singapore Eye Research Institute
- University or hospital
- Medicinski Fakultet, Sveučilište u Zagrebu
- University or hospital
- Helmholtz Zentrum München
- Government
- National Heart, Lung, and Blood Institute
- Government
- National Center for Research Resources
- Government
- National Center for Advancing Translational Sciences
- Government
- NHLBI NIH HHS
- Government
- NCRR NIH HHS
- Government
- NCATS NIH HHS
- Grants
- National Heart, Lung, and Blood Institute (U01-HL-041652); National Heart, Lung, and Blood Institute (U01 HL041642); National Heart, Lung, and Blood Institute (R01-HL109319); National Center for Advancing Translational Sciences (UL1TR001409); National Heart, Lung, and Blood Institute (U01 HL065521); National Center for Research Resources (M01RR000047); National Heart, Lung, and Blood Institute (U01 HL-041654); National Heart, Lung, and Blood Institute (R01HL109284)
Based on 11 listed funder(s).
Publication
- Published
- 2017-04-11 · J Hypertens · vol. 35 · issue 9 · pp. 1794–1800
- Publisher
- Lippincott Williams & Wilkins
- Cited
- 15 citations · more than 81% of similar papers · 1.2× the field average
- References
- 48 works
- Access
- Open access (repository copy)
- Research areas
- Nutritional Studies and Diet · Meat and Animal Product Quality · Agriculture Sustainability and Environmental Impact
- Keywords
- Medicine, Red meat, Internal medicine, Cardiology, Processed meat, Disease, Heart disease, Prospective cohort study, Pathology, Food science
- MeSH
- humans, cardiovascular diseases, hypertension, diet, prospective studies, adult, indians, north american, red meat
8 authors
From US, DE
- Bernhard Haring · correspondingCornell University; University of Würzburg; University of Oklahoma Health Sciences Center
- Wenyu WangUniversity of Oklahoma Health Sciences Center
- Amanda M. FrettsUniversity of Washington
- Daichi ShimboColumbia University Irving Medical Center
- Elisa T. LeeUniversity of Oklahoma Health Sciences Center
- Barbara V. HowardMedStar Health
Abstract
Objective
The aim of this study was to investigate whether red meat consumption is related to changes in left ventricular mass (LVM), left atrial diameter and carotid atherosclerosis in American Indians.
Methods
We prospectively analyzed echocardiographic and carotid ultrasound data of 1090 adults aged 40 years and older enrolled in the Strong Heart Family Study who were free of cardiovascular disease at baseline - 535 (49%) were hypertensive and 555 (51%) participants were nonhypertensive. Processed and unprocessed red meat intake was ascertained by using a Block food-frequency questionnaire at baseline. Cardiac and vascular biomarkers were assessed at baseline and 4 years later. Marginal models with multivariate adjustment were used to assess the associations of red meat intake with LVM, left atrial diameter, intima-media thickness and presence and extent of carotid atherosclerosis.
Results
Participants with hypertension were older, had a higher BMI, were more likely to be diabetic and less physically active. Processed and unprocessed red meat consumption was related to an increase in the presence of atherosclerotic plaques in male and female hypertensive individuals. In male hypertensive participants, processed meat intake was further observed to be associated with an increase in intima-media thickness, atrial diameter but not LVM. In nonhypertensive participants, neither unprocessed nor processed red meat intake was associated with changes in cardiac parameters or carotid atherosclerosis.
Conclusion
Over a 4-year period, red meat consumption was related to cardiovascular target organ damage in hypertensive American Indians. These findings emphasize the importance of dietary measures for cardiovascular disease prevention.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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