Cross-sectional study2017Industry fundedOpen access

Funded in part by Danone, Instituto Danone, Danone Institute China

Hydration, Fluid Intake, and Related Urine Biomarkers among Male College Students in Cangzhou, China: A Cross-Sectional Study-Applications for Assessing Fluid Intake and Adequate Water Intake

Zhang N, Du S, Tang Z, Zheng M, Yan R, Zhu Y, Ma G

International journal of environmental research and public health · 36 citations

Review labels

Industry funded

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cross-sectional study (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Industry funded
Company
Danone
Company
Instituto Danone
Company
Danone Institute China

Based on 3 listed funder(s) and full-text disclosure statement.

Publication

Published
2017-05-11 · Int J Environ Res Public Health · vol. 14 · issue 5 · p. 513
Publisher
Multidisciplinary Digital Publishing Institute
Cited
50 citations · more than 88% of similar papers · 2.4× the field average
References
41 works
Access
Open access (journal) · CC-BY
Research areas
Thermoregulation and physiological responses · Body Composition Measurement Techniques · Muscle metabolism and nutrition
Keywords
Fluid intake, Urine, Urine osmolality, Urine specific gravity, Medicine, Urinalysis, Cross-sectional study, Water intake, Body fluid, Physiology, Animal science, Internal medicine, Biology, Pathology
MeSH
humans, cross-sectional studies, water-electrolyte balance, drinking, eating, osmolar concentration, specific gravity, adolescent, adult, china, male, young adult, biomarkers

7 authors

From CN

  • Na ZhangPeking University
  • Songming DuChinese Nutrition Society
  • Zhenchuang Tang
  • Mengqi ZhengChinese Center For Disease Control and Prevention; National Institute for Nutrition and Health
  • Ruixia Yan
  • Yi-Tang ZhuCangzhou Central Hospital

Abstract

The objectives of this study were to assess the associations between fluid intake and urine biomarkers and to determine daily total fluid intake for assessing hydration status for male college students. A total of 68 male college students aged 18-25 years recruited from Cangzhou, China completed a 7-day cross-sectional study. From day 1 to day 7; all subjects were asked to complete a self-administered 7-day 24-h fluid intake record. The foods eaten by subjects were weighed and 24-h urine was collected for three consecutive days on the last three consecutive days. On the sixth day, urine osmolality, specific gravity (USG), pH, and concentrations of potassium, sodium, and chloride was determined. Subjects were divided into optimal hydration, middle hydration, and hypohydration groups according to their 24-h urine osmolality. Strong relationships were found between daily total fluid intake and 24-h urine biomarkers, especially for 24-h urine volume (r = 0.76; p r = 0.76; p R²) explained by PLS (partial least squares) model with seven urinary biomarkers was 68.9%; two urine biomarkers-24-h urine volume and osmolality-were identified as possible key predictors. The daily total fluid intake for assessing optimal hydration was 2582 mL, while the daily total fluid intake for assessing hypohydration was 2502 mL. Differences in fluid intake and urine biomarkers were found among male college students with different hydration status. A strong relationship existed between urine biomarkers and fluid intake. A PLS model identified that key variables for assessing daily total fluid intake were 24-h urine volume and osmolality. It was feasibility to use total fluid intake to judge hydration status.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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