Study2017

A study of glycaemic effects following acute anthocyanin-rich blueberry supplementation in healthy young adults

Bell L, Lamport DJ, Butler LT, Williams CM

Food & function · 46 citations

Review labels

Controlled feeding

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Randomized controlled trial (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Food provided by researchers

Who paid for it

Funding
Independent funding
Government
Economic and Social Research Council
Grants
Economic and Social Research Council (1371582)

Based on 1 listed funder(s).

Publication

Published
2017-01-01 · Food Funct · vol. 8 · issue 9 · pp. 3104–3110
Publisher
Royal Society of Chemistry
Cited
73 citations · more than 95% of similar papers · 4.0× the field average
Impact
Top 10% most cited in its field
References
52 works
Access
Open access (hybrid journal) · CC-BY
Research areas
Phytochemicals and Antioxidant Activities · Biochemical Analysis and Sensing Techniques · Natural Antidiabetic Agents Studies
Keywords
Postprandial, Anthocyanin, Type 2 diabetes, Diabetes mellitus, Medicine, Sugar, Blood sugar, Internal medicine, Carbohydrate, Endocrinology, Food science, Chemistry
MeSH
humans, fruit, hyperglycemia, anthocyanins, blood glucose, hypoglycemic agents, dietary supplements, adult, male, young adult, blueberry plants

4 authors

From GB

  • Lynne BellReading Museum; University of Reading
  • Daniel Joseph LamportReading Museum; University of Reading
  • Laurie T. ButlerReading Museum; University of Reading
  • Claire Michelle Williams · correspondingReading Museum; University of Reading

Abstract

The postprandial response to ingested carbohydrate is recognised as a marker of metabolic health. Postprandial hyperglycaemia is observed in type 2 diabetes mellitus and is a significant risk factor for cardiovascular disease. Cognitive deficits are also associated with type 2 diabetes. Therefore interventions which moderate postprandial glucose profiles are desirable. Here we investigated the impact of anthocyanin-rich wild blueberries on postprandial glucose response. Seventeen healthy young adults consumed a range of doses of freeze-dried wild blueberry powder, in smoothie form, in both sugar-matched and no-added-sugar conditions. Plasma glucose was determined by a capillary sampling method at baseline and at regular intervals up to 2.5 hours postprandially. Blueberries were observed to significantly extend the postprandial glucose response beyond the period observed for a sugar-matched control, characteristic of a beneficial glycaemic response. Furthermore, blueberries were observed to reduce peak postprandial glucose levels, although statistical significance was not achieved. The findings suggest a tempering of the postprandial glucose response in the presence of anthocyanin-rich blueberry, and are discussed with reference to likely glucoregulatory mechanisms of action and their implications for cognitive and type 2 diabetes research.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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