Performance and Health Benefits of Dietary Nitrate Supplementation in Older Adults: A Systematic Review
Stanaway L, Rutherfurd-Markwick K, Page R, Ali A
Nutrients · 47 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Systematic review (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2017-10-27 · Nutrients · vol. 9 · issue 11 · p. 1171
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 59 citations · more than 83% of similar papers · 1.7× the field average
- References
- 32 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Cardiovascular and exercise physiology · Nitric Oxide and Endothelin Effects · Heart Rate Variability and Autonomic Control
- Keywords
- Medicine, Crossover study, Blood pressure, Effects of sleep deprivation on cognitive performance, Health benefits, Nutritional Supplementation, Randomized controlled trial, Cardiovascular health, Cognition, Disease, Gerontology, Physical therapy, Internal medicine, Alternative medicine, Placebo, Traditional medicine
- MeSH
- humans, beta vulgaris, cardiovascular diseases, metabolic diseases, nitrates, nitric oxide, cognition, aging, blood pressure, cerebrovascular circulation, dietary supplements, aged, female, male
4 authors
From NZ
- Luke StanawayMassey University
- Kay Janice Rutherfurd-MarkwickMassey University
- Rachel PageMassey University
- Ajmol Ali · correspondingMassey University
Abstract
Supplementation with nitrate (NO₃-)-rich beetroot juice has been shown to improve exercise performance and cardiovascular (CV) responses, due to an increased nitric oxide (NO) availability. However, it is unclear whether these benefits are greater in older adults who have an age-related decrease in NO and higher risk of disease. This systematic review examines 12 randomised, crossover, control trials, investigating food-based NO₃- supplementation in older adults and its potential benefits on physiological and cognitive performances, and CV, cerebrovascular and metabolic health. Four studies found improvements in physiological performance (time to exhaustion) following dietary NO₃- supplementation in older adults. Benefits on cognitive performance were unclear. Six studies reported improvements in CV health (blood pressure and blood flow), while six found no improvement. One study showed improvements in cerebrovascular health and two found no improvement in metabolic health. The current literature indicates positive effects of dietary NO₃- supplementation in older adults on physiological performance, with some evidence indicating benefits on cardiovascular and cerebrovascular health. Effects on cognitive performance were mixed and studies on metabolic health indicated no benefit. However, there has been limited research conducted on the effects of dietary NO₃- supplementation in older adults, thus, further study, utilising a randomised, double-blind, control trial design, is warranted.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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