Acute effect of dietary nitrate on forearm muscle oxygenation, blood volume and strength in older adults: A randomized clinical trial
de Oliveira GV, Morgado M, Conte-Junior CA, Alvares TS
PloS one · 20 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food provided by researchers
Who paid for it
- Funding
- Independent funding
- Government
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Government
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Grants
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (2014‐0); Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (E-26/); Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (E-26/110.309/2014); Conselho Nacional de Desenvolvimento Científico e Tecnológico (442977/2014-0)
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2017-11-30 · PLoS One · vol. 12 · issue 11 · p. e0188893
- Publisher
- Public Library of Science
- Cited
- 30 citations · more than 96% of similar papers · 5.8× the field average
- Impact
- Top 10% most cited in its field
- References
- 44 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Cardiovascular and exercise physiology · Heart Rate Variability and Autonomic Control · High Altitude and Hypoxia
- Keywords
- Medicine, Oxygenation, Forearm, Randomized controlled trial, Cardiology, Internal medicine, Blood pressure, Surgery
- MeSH
- muscle, skeletal, humans, nitrates, oxygen, hand strength, diet, cross-over studies, double-blind method, blood volume, aged, female, male, muscle strength
4 authors
From BR
- Gustavo Vieira de OliveiraUniversidade Federal do Rio de Janeiro
- Marina MorgadoUniversidade Federal do Rio de Janeiro
- Carlos Adam Conte‐JúniorUniversidade Federal Fluminense
- Thiago Silveira Álvares · correspondingUniversidade Federal do Rio de Janeiro
Abstract
Both recovery time of post-exercise muscle oxygenation and muscle strength decline with aging. Although beetroot consumption has been shown to improve muscle oxygenation and exercise performance in adults, these effects in the elderly has not been addressed. The aim of the present study was to evaluate the effect of a beetroot-based gel (BG) on muscle O2 saturation, blood volume (tHb) and handgrip strength in the elderly in response to handgrip exercise. In a randomized crossover double-blind design, twelve older subjects consumed BG (100 g of beetroot-based gel containing ~ 12 mmol nitrate) or PLA (100 g of nitrate-depleted gel nitrate-depleted). The subjects performed a rhythmic handgrip exercise which consisted of a one 1-min set at 30% of the maximal voluntary contraction (MVC) of each subject, followed by a 1 min recovery. The muscle oxygenation parameters and tHb were continuously monitored by using near-infrared spectroscopy. MVC was evaluated at baseline, immediately after exercise, and 30 min afterwards. The muscle O2 resaturation rate during exercise recovery was greater in the BG when compared to PLA condition (1.43 ± 0.77 vs 1.02 ± 0.48%.s-1; P < 0.05). Significant increase was observed in tHb during exercise recovery (10.25 ± 5.47 vs 6.72 ± 4.55 μM; P < 0.05) and significant reduction of handgrip strength decline was observed 30 min after exercise in BG (- 0.24 ± 0.18 vs-0.39 ± 0.20 N; P < 0.05). In summary, a single dose of a beetroot-based gel speeds up muscle O2 resaturation, increases blood volume and improves recovery of handgrip strength after handgrip exercise in older adults.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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