Randomized controlled trial2017Industry fundedOpen access

Funded in part by California Walnut Commission

Walnut consumption in a weight reduction intervention: effects on body weight, biological measures, blood pressure and satiety

Rock CL, Flatt SW, Barkai HS, Pakiz B, Heath DD

Nutrition journal · 50 citations

Review labels

Industry funded

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Not stated

Who paid for it

Funding
Industry funded
Nonprofit
American Institute for Cancer Research
Industry group
California Walnut Commission

Based on 2 listed funder(s) and full-text disclosure statement.

Publication

Published
2017-12-01 · Nutr J · vol. 16 · issue 1 · p. 76
Publisher
BioMed Central
Cited
77 citations · more than 95% of similar papers · 4.2× the field average
Impact
Top 10% most cited in its field
References
39 works
Access
Open access (journal) · CC-BY
Research areas
Nuts composition and effects · Agriculture Sustainability and Environmental Impact · Body Composition Measurement Techniques
Keywords
Medicine, Clinical nutrition, Weight loss, Body weight, Blood pressure, Reduction (mathematics), Consumption (sociology), Obesity, Internal medicine
MeSH
humans, juglans, nuts, obesity, body weight, weight loss, body mass index, diet, reducing, satiation, behavior therapy, energy intake, blood pressure, middle aged, female, male, overweight, cholesterol, ldl, waist circumference

5 authors

From US

  • Cheryl L. Rock · correspondingUniversity of California San Diego
  • Shirley W. FlattUniversity of California San Diego
  • Hava‐Shoshana BarkaiUniversity of California San Diego
  • Bilgé PakizUniversity of California San Diego
  • Dennis D. HeathUniversity of California San Diego

Abstract

Background

Dietary strategies that help patients adhere to a weight reduction diet may increase the likelihood of weight loss maintenance and improved long-term health outcomes. Regular nut consumption has been associated with better weight management and less adiposity. The objective of this study was to compare the effects of a walnut-enriched reduced-energy diet to a standard reduced-energy-density diet on weight, cardiovascular disease risk factors, and satiety.

Methods

Overweight and obese men and women (n = 100) were randomly assigned to a standard reduced-energy-density diet or a walnut-enriched (15% of energy) reduced-energy diet in the context of a behavioral weight loss intervention. Measurements were obtained at baseline and 3- and 6-month clinic visits. Participants rated hunger, fullness and anticipated prospective consumption at 3 time points during the intervention. Body measurements, blood pressure, physical activity, lipids, tocopherols and fatty acids were analyzed using repeated measures mixed models.

Results

Both study groups reduced body weight, body mass index and waist circumference (time effect p < 0.001 for each). Change in weight was -9.4 (0.9)% vs. -8.9 (0.7)% (mean [SE]), for the standard vs. walnut-enriched diet groups, respectively. Systolic blood pressure decreased in both groups at 3 months, but only the walnut-enriched diet group maintained a lower systolic blood pressure at 6 months. The walnut-enriched diet group, but not the standard reduced-energy-density diet group, reduced total cholesterol and low-density lipoprotein cholesterol (LDL-C) at 6 months, from 203 to 194 mg/dL and 121 to 112 mg/dL, respectively (p < 0.05). Self-reported satiety was similar in the groups.

Conclusions

These findings provide further evidence that a walnut-enriched reduced-energy diet can promote weight loss that is comparable to a standard reduced-energy-density diet in the context of a behavioral weight loss intervention. Although weight loss in response to both dietary strategies was associated with improvements in cardiovascular disease risk factors, the walnut-enriched diet promoted more favorable effects on LDL-C and systolic blood pressure.

Trial registration

The trial is registered at ( NCT02501889 ).

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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