Randomized controlled trial2017

Caffeine effects on VO2max test outcomes investigated by a placebo perceived-as-caffeine design

Brietzke C, Asano RY, De Russi de Lima F, Pinheiro FA, Franco-Alvarenga, Ugrinowitsch C, Pires FO

Nutrition and health · 22 citations

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
Government
Fundação de Amparo à Pesquisa do Estado de São Paulo
Government
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Government
Fundacao de Amparo a Pesquisa do Estado de Sao Paulo
Grants
Fundação de Amparo à Pesquisa do Estado de São Paulo (2010/01317-0)

Based on 3 listed funder(s).

Publication

Published
2017-12-01 · Nutr Health · vol. 23 · issue 4 · pp. 231–238
Publisher
SAGE Publishing
Cited
30 citations · more than 70% of similar papers · 0.8× the field average
References
49 works
Access
Paywalled
Research areas
Muscle metabolism and nutrition · Cardiovascular and exercise physiology · Sports Performance and Training
Keywords
Caffeine, Placebo, Ingestion, Perceived exertion, Medicine, VO2 max, Internal medicine, Cycling, Endocrinology, Animal science, Cardiology, Physical therapy, Heart rate, Blood pressure, Biology
MeSH
leg, humans, fatigue, caffeine, central nervous system stimulants, severity of illness index, reproducibility of results, single-blind method, attitude to health, deception, oxygen consumption, time factors, bicycling, dietary supplements, adult, athletic performance, physical exertion, young adult, performance-enhancing substances, musculoskeletal pain

7 authors

From BR

  • Cayque BrietzkeUniversidade de São Paulo
  • Ricardo Yukio AsanoUniversidade de São Paulo
  • Felipe De Russi de LimaUniversidade de São Paulo
  • Fabiano Aparecido PinheiroUniversidade de São Paulo
  • Paulo Estevão Franco‐AlvarengaUniversidade de São Paulo
  • Carlos UgrinowitschUniversidade de São Paulo

Abstract

Background

Ergogenic effects of caffeine (CAF) ingestion have been observed in different cycling exercise modes, and have been associated with alterations in ratings of perceived exertion (RPE). However, there has been little investigation of maximal oxygen uptake (VO2MAX) test outcomes.

Aim

This study aimed to verify whether CAF may reduce RPE, thereby improving maximal incremental test (MIT) outcomes such as VO2MAX, time to exhaustion and peak power output (WPEAK).

Methods

Nine healthy individuals performed three MITs (25 W/min until exhaustion) in a random, counterbalanced fashion after ingestion of CAF, placebo perceived as caffeine (PLA), and no supplementation (baseline control). VO2 was measured throughout the test, while RPE was rated according to overall and leg effort sensations. The power output corresponding to submaximal (RPE = 14 according to the 6-20 Borg scale) and maximal RPE was recorded for both overall (O-RPE14 and O-RPEMAX) and leg RPE (L-RPE14 and L-RPEMAX).

Results

VO2MAX did not change significantly between MITs; however, CAF and PLA increased time to exhaustion (↑ ∼18.7% and ∼17.1%, respectively; p PEAK (↑ ∼13.0% and ∼11.8%, respectively; p MAX and L-RPEMAX) than submaximal RPE (possibly beneficial in O-RPE14 and L-RPE14). Similar results were found when participants ingested PLA.

Conclusions

Compared with control, CAF and PLA improved MIT performance outcomes such as time to exhaustion and WPEAK, without altering VO2MAX values. CAF effects were attributed to placebo.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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