Low 25-hydroxyvitamin D levels in postmenopausal female patients with benign paroxysmal positional vertigo
Han W, Fan Z, Zhou M, Guo X, Yan W, Lu X, Li L, Gu C, Chen C, Wu Y
Acta oto-laryngologica · 30 citations
How it was studied
- Design
- Case-control study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- University or hospital
- Zhejiang Province Regional Center for Neurology
Based on 1 listed funder(s).
Publication
- Published
- 2017-12-22 · Acta Otolaryngol · vol. 138 · issue 5 · pp. 443–446
- Publisher
- Taylor & Francis
- Cited
- 41 citations · more than 90% of similar papers · 2.5× the field average
- References
- 20 works
- Access
- Paywalled
- Research areas
- Vestibular and auditory disorders · Balance, Gait, and Falls Prevention · Temporomandibular Joint Disorders
- Keywords
- Medicine, Benign paroxysmal positional vertigo, Odds ratio, Vitamin D and neurology, Confidence interval, Internal medicine, vitamin D deficiency, Vertigo, Postmenopausal women, Bone mineral, Gastroenterology, Endocrinology, Osteoporosis, Surgery
- MeSH
- humans, vitamin d deficiency, vitamin d, logistic models, retrospective studies, postmenopause, bone density, adult, aged, aged, 80 and over, middle aged, female, benign paroxysmal positional vertigo
10 authors
From CN
- Weiwei HanNingbo No. 2 Hospital
- Zhenyi FanNingbo No. 2 Hospital
- Min ZhouNingbo No. 2 Hospital
- Xu GuoNingbo No. 2 Hospital
- Yan WangNingbo No. 2 Hospital
- Xiaoxiong LuNingbo No. 2 Hospital
Abstract
Objective
Several studies have reported the association of benign paroxysmal positional vertigo (BPPV) with vitamin D deficiency. This study aimed to evaluate serum 25-hydroxy vitamin D (25 (OH) D) levels in native Chinese postmenopausal women with de novo idiopathic BPPV and to investigate the possible relationship between the occurrence of BPPV and low 25 (OH) D levels.
Methods
This retrospective study comprised of 85 postmenopausal women with de novo idiopathic BPPV and 80 age-matched healthy controls. All subjects had bone mineral density (BMD) and serum 25 (OH) D levels measurements recorded, and the results were compared.
Results
The prevalence of reduced BMD (T score <-1.0) was significantly higher in female patients with BPPV than in healthy controls (71.8% vs. 51.2%, p = .004). The mean serum 25 (OH) D levels were also significantly lower in female patients with BPPV than in healthy controls (19.1 ± 5.2 vs. 22.5 ± 5.8, p < .001). The regression analyses demonstrated that vitamin D deficiency was associated with BPPV with an odds ratio of 2.1 (95% confidence interval = 1.1-3.1, p = .031).
Conclusion
Our study suggests that low 25 (OH) D may be a risk factor for BPPV in postmenopausal women.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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