Effects of blueberry and cranberry consumption on type 2 diabetes glycemic control: A systematic review
Rocha DMUP, Caldas APS, da Silva BP, Hermsdorff HHM, Alfenas RCG
Critical reviews in food science and nutrition · 40 citations
How it was studied
- Design
- Systematic review (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Government
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Government
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais
- Government
- Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico
- Government
- Coordenação de Aperfeiçoamento de Pessoal de NÃvel Superior
- Government
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais
Based on 6 listed funder(s).
Publication
- Published
- 2018-01-18 · Crit Rev Food Sci Nutr · vol. 59 · issue 11 · pp. 1816–1828
- Publisher
- Taylor & Francis
- Cited
- 67 citations · more than 87% of similar papers · 1.8× the field average
- References
- 74 works
- Access
- Paywalled
- Research areas
- Natural Antidiabetic Agents Studies · Phytochemicals and Antioxidant Activities · Diet, Metabolism, and Disease
- Keywords
- Glycemic, Type 2 diabetes, Diabetes mellitus, Medicine, Food science, Sweetening agents, Chemistry, Endocrinology
- MeSH
- animals, humans, vaccinium macrocarpon, fruit, diabetes mellitus, type 2, anthocyanins, blood glucose, plant extracts, complementary therapies, phytotherapy, dietary supplements, databases, factual, randomized controlled trials as topic, polyphenols, blueberry plants
5 authors
From BR
- Daniela Mayumi Usuda Prado Rocha · correspondingUniversidade Federal de Viçosa
- Ana Paula Silva CaldasUniversidade Federal de Viçosa
- Bárbara Pereira da SilvaUniversidade Federal de Viçosa
- Helen Hermana Miranda HermsdorffUniversidade Federal de Viçosa
- Rita de Cássia Gonçalves AlfenasUniversidade Federal de Viçosa
Abstract
The metabolic effects of cranberry and blueberry consumption on glycemic control have been evaluated in vitro and in animal models as well as in human studies, although findings have not been systematically reviewed yet. Therefore, a systematic review was carried out of relevant randomized clinical trials (RCTs) in order to assess the effect of berries (blueberry and cranberry) consumption on type 2 diabetes (T2DM) glycemic control. Some evidences were also discussed on the anti-diabetic mechanisms exerted by berries polyphenols. Studies were identified by searching electronic databases: LILACS, PubMed/MEDLINE, Scopus, The Cochrane Library and Web of Science. Three authors independently searched and extracted RCTs in which the effect of berries (cranberry or blueberry) consumption on T2DM glycemic control was assessed. A total of 7 RCTs, involving 270 adults with type 2 diabetes were included. Despite the heterogeneity of the administration forms (in natura, dried, extract, preparations - juice), dosage, duration of the intervention and type of population of the studies involving these two berries some studies highlight the potential benefit of berries, especially of blueberry, on glucose metabolism in T2DM subjects. Daily cranberry juice (240 mL) consumption for 12 weeks and blueberry extract or powder supplementation (9.1 to 9.8 mg of anthocyanins, respectively) for 8 to 12 weeks showed a beneficial effect on glucose control in T2DM subjects. Those results indicate a promising use of these berries in T2DM management; although more studies are required to better understand the mechanisms involved.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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