Dietary Magnesium Intake and Hyperuricemia among US Adults
Zhang Y, Qiu H
Nutrients · 36 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2018-03-02 · Nutrients · vol. 10 · issue 3 · p. 296
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 64 citations · more than 78% of similar papers · 1.5× the field average
- References
- 48 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Gout, Hyperuricemia, Uric Acid · Magnesium in Health and Disease · Omental and Epiploic Conditions
- Keywords
- Hyperuricemia, Medicine, Magnesium, Physiology, Endocrinology, Internal medicine, Food science, Environmental health, Biology, Uric acid, Chemistry
- MeSH
- humans, hyperuricemia, magnesium, uric acid, diet, nutrition surveys, multivariate analysis, logistic models, odds ratio, risk factors, cross-sectional studies, nutritional status, adult, aged, aged, 80 and over, middle aged, united states, female, male, young adult, recommended dietary allowances, protective factors, biomarkers
2 authors
From CN
- Yiying ZhangJiamusi University; Harbin Medical University
- Hongbin Qiu · correspondingJiamusi University; Harbin Medical University
Abstract
To assess the association between dietary magnesium intake and hyperuricemia in United States (US) adults, we extracted 26,796 US adults aged 20-85 years from the National Health and Nutrition Examination Survey (NHANES) in 2001-2014. All dietary intake was measured through 24 h dietary recall method. Multivariable logistic regression analysis was performed to investigate the association between magnesium intake and hyperuricemia after adjusting for several important confounding variables. When compared to the lowest quintile (Q1), for male, adjusted odds ratios (ORs) of hyperuricemia in the second quintile (Q2) to the fifth quintile (Q5) of the magnesium intake were 0.83 (95% CI: 0.72-0.95), 0.74 (0.64-0.85), 0.78 (0.67-0.90), and 0.70 (0.58-0.84, p for trend = 0.0003), respectively. For female, OR was 0.75 (0.62-0.90) in the fourth quintile (Q4) (p for trend = 0.0242). As compared to Q4 of magnesium intake (contains recommended amount), the relative odds of hyperuricemia were increased by 1.29 times in Q1 (OR = 1.29, 1.11-1.50) in male. The ORs were 1.33 (1.11-1.61) in Q1, 1.27 (1.07-1.50) in Q2 in female. Our results indicated that increased magnesium intake was associated with decreased hyperuricemia risk. It also indicated the importance of recommended dietary allowance (RDA) of magnesium and the potential function of magnesium intake in the prevention of hyperuricemia.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.