Meta-analysis2018Open access

Meta-analysis evaluating music interventions for anxiety and pain in surgery

Kühlmann AYR, de Rooij A, Kroese LF, van Dijk M, Hunink MGM, Jeekel J

The British journal of surgery · 283 citations

How it was studied

Design
Meta-analysis (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
University or hospital
University of Cambridge
Government
ZonMw
Nonprofit
Stichting Swart-van Essen
Nonprofit
Stichting Coolsingel
Nonprofit
Stichting Coolsingel, Rotterdam, The Netherlands
Nonprofit
Stichting Swart-van Essen, Rotterdam, The Netherlands

Based on 6 listed funder(s) and full-text disclosure statement.

Publication

Published
2018-04-17 · Br J Surg · vol. 105 · issue 7 · pp. 773–783
Publisher
Oxford University Press
Cited
429 citations · more than 100% of similar papers · 28.9× the field average
Impact
Top 10% most cited in its field
References
132 works
Access
Open access (hybrid journal) · CC-BY-NC-ND
Research areas
Music Therapy and Health · Intensive Care Unit Cognitive Disorders · Dental Anxiety and Anesthesia Techniques
Keywords
Medicine, Anxiety, Psychological intervention, Meta-analysis, Perioperative, Music therapy, Subgroup analysis, Visual analogue scale, Randomized controlled trial, Physical therapy, MEDLINE, Anesthesia, Internal medicine, Psychiatry
MeSH
humans, pain measurement, music therapy, anxiety, adult, postoperative pain

6 authors

From NL, US

  • A. Y. Rosalie Kühlmann · correspondingErasmus MC - Sophia Children’s Hospital
  • A. de RooijErasmus University Rotterdam
  • Leonard Frederik KroeseErasmus University Rotterdam
  • Monique van DijkErasmus MC - Sophia Children’s Hospital; Erasmus University Rotterdam
  • M. G. Myriam HuninkHarvard University; Erasmus University Rotterdam
  • J JeekelErasmus University Rotterdam

Abstract

Background

This study aimed to evaluate anxiety and pain following perioperative music interventions compared with control conditions in adult patients.

Methods

Eleven electronic databases were searched for full-text publications of RCTs investigating the effect of music interventions on anxiety and pain during invasive surgery published between 1 January 1980 and 20 October 2016. Results and data were double-screened and extracted independently. Random-effects meta-analysis was used to calculate effect sizes as standardized mean differences (MDs). Heterogeneity was investigated in subgroup analyses and metaregression analyses. The review was registered in the PROSPERO database as CRD42016024921.

Results

Ninety-two RCTs (7385 patients) were included in the systematic review, of which 81 were included in the meta-analysis. Music interventions significantly decreased anxiety (MD -0·69, 95 per cent c.i. -0·88 to -0·50; P < 0·001) and pain (MD -0·50, -0·66 to -0·34; P < 0·001) compared with controls, equivalent to a decrease of 21 mm for anxiety and 10 mm for pain on a 100-mm visual analogue scale. Changes in outcome corrected for baseline were even larger: MD -1·41 (-1·89 to -0·94; P < 0·001) for anxiety and -0·54 (-0·93 to -0·15; P = 0·006) for pain. Music interventions provided during general anaesthesia significantly decreased pain compared with that in controls (MD -0·41, -0·64 to -0·18; P < 0·001). Metaregression analysis found no significant association between the effect of music interventions and age, sex, choice and timing of music, and type of anaesthesia. Risk of bias in the studies was moderate to high.

Conclusion

Music interventions significantly reduce anxiety and pain in adult surgical patients.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).

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