Association of High Cardiovascular Fitness and the Rate of Adaptation to Heat Stress
Żychowska M, Nowak-Zaleska A, Chruściński G, Zaleski R, Mieszkowski J, Niespodziński B, Tymański R, Kochanowicz A
BioMed research international · 7 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Independent funding
- Government
- Ministerstwo Edukacji i Nauki
- Government
- Ministerstwo Nauki i Szkolnictwa Wyzszego
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2018-01-01 · Biomed Res Int · vol. 2018 · pp. 1–6
- Publisher
- Hindawi Publishing Corporation
- Cited
- 14 citations · more than 84% of similar papers · 1.8× the field average
- References
- 24 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Exercise and Physiological Responses · Thermoregulation and physiological responses · Adipose Tissue and Metabolism
- Keywords
- Adaptation (eye), Heat stress, Association (psychology), Stress (linguistics), Biology, Medicine, Psychology, Neuroscience, Animal science
- MeSH
- cardiovascular system, humans, rna, messenger, interleukin-6, interleukin-10, adaptation, physiological, apoptosis, gene expression, heat-shock response, adult, male, hsp70 heat-shock proteins, hot temperature, hsp27 heat-shock proteins, young adult
8 authors
From PL
- Małgorzata Żychowska · correspondingGdansk University of Physical Education and Sport
- Alicja Nowak-ZaleskaUniversity of Gdańsk; Gdansk University of Physical Education and Sport
- Grzegorz ChruścińskiGdansk University of Physical Education and Sport
- Ryszard Zaleski
- Jan MieszkowskiKazimierz Wielki University in Bydgoszcz
- Bartłomiej NiespodzińskiKazimierz Wielki University in Bydgoszcz
Abstract
This study aimed to compare changes in genes expression associated with inflammation and apoptosis in response to heat stress caused by sauna between people with varying cardiorespiratory fitness levels. We hypothesis that high cardiorespiratory level caused higher positive changes after four weeks of sauna bathing. Blood samples were taken at rest before and after the first and last sauna sessions and 48 hours after the last sauna session and used to assay HSP70 (HSPA1A), HSP27 (HSPB1), interleukin 6 (IL6), and interleukin 10 (IL10) genes expression in blood with quantitative real-time qRT-PCR. Overall, small decreases in rest values of HSPA1A and IL6 mRNA, increase in HSPB1 mRNA, and a significant increase in IL10 mRNA were observed after four weeks of exposure to heat stress. Our findings suggest that an adaptive response to heat stress (an anti-inflammatory response) occurs faster in people with higher cardiorespiratory fitness.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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