Randomized controlled trial2018

Impact of Diets Rich in Whole Grains and Fruits and Vegetables on Cardiovascular Risk Factors in Overweight and Obese Women: A Randomized Clinical Feeding Trial

Fatahi S, Daneshzad E, Kord-Varkaneh H, Bellissimo N, Brett NR, Azadbakht L

Journal of the American College of Nutrition · 31 citations

Review labels

Controlled feeding

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Food provided by researchers

Who paid for it

Funding
Independent funding
University or hospital
Isfahan University of Medical Sciences
Government
U.S. Food and Drug Administration
University or hospital
University of Medical Sciences, Isfahan, Iran

Based on 3 listed funder(s).

Publication

Published
2018-04-27 · J Am Coll Nutr · vol. 37 · issue 7 · pp. 568–577
Publisher
Taylor & Francis
Cited
41 citations · more than 92% of similar papers · 3.3× the field average
Impact
Top 10% most cited in its field
References
77 works
Access
Paywalled
Research areas
Food composition and properties · Nutritional Studies and Diet · Consumer Attitudes and Food Labeling
Keywords
Overweight, Waist, Medicine, Blood pressure, Obesity, Weight loss, Randomized controlled trial, Internal medicine
MeSH
humans, fruit, vegetables, cardiovascular diseases, obesity, diet, risk factors, blood pressure, adolescent, adult, middle aged, female, overweight, young adult, whole grains

6 authors

From IR, CA

  • Somaye FatahiTehran University of Medical Sciences
  • Elnaz DaneshzadTehran University of Medical Sciences
  • Hamed Kord‐VarkanehTehran University of Medical Sciences
  • Nick BellissimoToronto Metropolitan University
  • Neil R. BrettToronto Metropolitan University
  • Leila Azadbakht · correspondingIsfahan University of Medical Sciences; Tehran University of Medical Sciences

Abstract

Objective

Previous interventions have reported desirable effects of diets rich in whole grains or rich in fruits and vegetables on cardiovascular disease (CVD) risk factors and weight management. However, data are lacking regarding the effect of these fiber sources separately. The aim of this randomized clinical feeding trial was to investigate the effects of fiber-rich diets with different sources of fiber (fruits, vegetables, and whole grains) on weight loss and CVD risk factors in overweight and obese women.

Methods

Overweight and obese women (N = 75) were randomized to one of three weight loss diets that were rich in whole grains, fruits and vegetables, or both for 10 weeks. Body weight, waist circumference, and risk factors of CVD were examined at baseline and 10 weeks.

Results

During the 10-week dietary intervention phase, the reductions in weight (p = 0.03), waist circumference (p = 0.001), systolic blood pressure (p = 0.04), fasting blood sugar (p = 0.03), and triglycerides (p = 0.001) were higher in the whole grains group compared with the fruits and vegetables group or the combination diet group. Also, the whole grain group had a greater increase (p = 0.01) in high-density lipoprotein cholesterol compared to the other groups. The change in other risk factors, including diastolic blood pressure and low-density lipoprotein cholesterol, was not different among the three diet groups. Within-group comparisons revealed significant reductions in weight, waist circumference, and fasting blood sugar in all groups. Only the fruits and vegetables group and the whole grains group had significant decreases in low-density lipoprotein cholesterol over 10 weeks (p ≤ 0.03).

Conclusions

This trial suggests that in overweight and obese women, a weight loss diet rich in whole grains may have a more beneficial effect on CVD risk factors than diets rich in fruits and vegetables or a combination of whole grains and fruits and vegetables.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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