Changes of Blood Pressure and Hemodynamic Parameters after Oral Magnesium Supplementation in Patients with Essential Hypertension-An Intervention Study
Banjanin N, Belojevic G
Nutrients · 14 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2018-05-08 · Nutrients · vol. 10 · issue 5 · p. 581
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 23 citations · more than 68% of similar papers · 0.7× the field average
- References
- 29 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments
- Keywords
- Medicine, Impedance cardiography, Hemodynamics, Cardiac index, Blood pressure, Vascular resistance, Cardiac output, Stroke volume, Cardiology, Heart rate, Internal medicine, Anesthesia, Essential hypertension, Stroke (engine)
- MeSH
- heart, humans, magnesium, antihypertensive agents, administration, oral, blood pressure, heart rate, adult, aged, middle aged, female, male, hemodynamics, young adult, essential hypertension
2 authors
From RS
- Nikolina Banjanin · correspondingUniversity of Belgrade
- Goran BelojevićUniversity of Belgrade
Abstract
The objective of this study was to examine the changes of blood pressure and hemodynamic parameters after oral magnesium supplementation in patients with essential hypertension. The single-arm non-blinded intervention study comprised 48 patients (19 men; 29 women) whose antihypertensive therapy was not changed for at least one month. The participants were asked to consume (daily at home) 300 mg of oral magnesium-oxide supplementation product for one month and to have their blood pressure and hemodynamic parameters (thoracic fluid content, stroke volume, stroke index, cardiac output, cardiac index, acceleration index, left cardiac work index and systemic vascular resistance index, heart rate) measured in the hospital before and after the intervention. Measurements were performed with impedance cardiography. After magnesium supplementation, systolic and diastolic pressures were significantly decreased (mean ± standard deviation (SD)/mmHg/from 139.7 ± 15.0 to 130.8 ± 13.4 and from 88.0 ± 10.4 to 82.2 ± 9.0, respectively; both p p < 0.05). The observed hemodynamic changes may explain lowering blood pressure after magnesium supplementation.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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