Funded in part by American Egg Board/Egg Nutrition Council
Dietary Cholesterol Intake Is Not Associated with Risk of Type 2 Diabetes in the Framingham Offspring Study
Baghdasarian S, Lin HP, Pickering RT, Mott MM, Singer MR, Bradlee ML, Moore LL
Nutrients · 8 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Food diaries or recalls
Who paid for it
- Funding
- Industry funded
- Government
- Centers for Disease Control and Prevention
- Government
- National Heart, Lung, and Blood Institute
- Industry group
- American Egg Board/Egg Nutrition Council
- Government
- NHLBI NIH HHS
- Grants
- National Heart, Lung, and Blood Institute (N01‐HC25195); National Heart, Lung, and Blood Institute (N01-HC-025195)
Based on 4 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2018-05-24 · Nutrients · vol. 10 · issue 6 · p. 665
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 16 citations · more than 83% of similar papers · 1.5× the field average
- References
- 35 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Diet and metabolism studies · Obesity, Physical Activity, Diet
- Keywords
- Impaired fasting glucose, Medicine, Framingham Risk Score, Offspring, Confounding, Type 2 diabetes, Diabetes mellitus, Internal medicine, Type 2 Diabetes Mellitus, Hazard ratio, Framingham Heart Study, Endocrinology, Environmental health, Impaired glucose tolerance, Confidence interval, Disease, Biology, Pregnancy
- MeSH
- humans, diabetes mellitus, type 2, blood glucose, cholesterol, dietary, prognosis, health surveys, proportional hazards models, risk factors, longitudinal studies, time factors, adult, middle aged, massachusetts, female, male, recommended dietary allowances, biomarkers, diet, healthy
7 authors
From US
- Siyouneh BaghdasarianBoston University
- Hsuan-Ping LinBoston University
- Richard Taylor PickeringBoston University
- Melanie M. MottBoston University
- Martha R. SingerBoston University
- M. Loring BradleeBoston University
Abstract
Identification of diet and lifestyle risk factors for prevention of type 2 diabetes mellitus (T2DM) is of great importance. The specific role of dietary cholesterol (DC) in T2DM risk is unclear. This study uses data from 2192 Framingham Offspring Study subjects to estimate the effects of DC alone and in combination with markers of a healthy diet and other lifestyle factors on fasting glucose and risk of T2DM or impaired fasting glucose (IFG) over 20 years of follow-up. Dietary data were derived from two sets of three-day food records. Statistical methods included mixed linear regression and Cox proportional hazard's modeling to adjust for confounding. There were no statistically significant differences in glucose levels over 20 years of follow-up across DC intake categories (.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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