Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis
Xu GZ, Jia J, Jin L, Li JH, Wang ZY, Cao DY
Pain research & management · 64 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- National Natural Science Foundation of China
- University or hospital
- Xi'an Medical University
- Government
- Shaanxi Province Natural Science Basic Research Foundation of China
- University or hospital
- Xi’an Medical University
- Grants
- National Natural Science Foundation of China (2016JM3015); National Natural Science Foundation of China (81671097)
Based on 4 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2018-01-01 · Pain Res Manag · vol. 2018 · pp. 1–13
- Publisher
- Hindawi Publishing Corporation
- Cited
- 126 citations · more than 97% of similar papers · 3.5× the field average
- Impact
- Top 10% most cited in its field
- References
- 71 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Temporomandibular Joint Disorders · Laser Applications in Dentistry and Medicine · Oral health in cancer treatment
- Keywords
- Meta-analysis, Medicine, Laser therapy, Low level laser therapy, Laser, Internal medicine, Physics, Optics
- MeSH
- humans, temporomandibular joint disorders, follow-up studies, randomized controlled trials as topic, laser therapy, visual analog scale, outcome assessment, health care
6 authors
From CN
- Gang-Zhu XuXi'an Medical University; Stomatology Hospital; Xi'an Jiaotong University
- Jie JiaXian Mental Health Center
- Jin LinXi'an Medical University
- Jia‐Heng LiStomatology Hospital; Xi'an Jiaotong University
- Zhanyue WangStomatology Hospital; Xi'an Jiaotong University
- Dong‐Yuan Cao · correspondingStomatology Hospital; Xi'an Jiaotong University
Abstract
Objectives
We systematically reviewed randomized controlled trials (RCTs) of the effect of low-level laser therapy (LLLT) versus placebo in patients with temporomandibular disorder (TMD).
Methods
A systematic search of multiple online sources electronic databases was undertaken. The methodological quality of each included study was assessed using the modified Jadad scale, and the quality of evidence was evaluated using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system.
Results
A total of 31 RCTs were included. Total modified Jadad scale scores showed that the methodological quality was high in 30 studies and low in 1 study. Combining data from all clinically heterogeneous studies revealed positive effects of LLLT on pain relief, regardless of the visual analogue scale (VAS) score or the change of VAS score between the baseline and the final follow-up time point, while dosage analyses showed discrepant results about the effects of high or low doses for patients with TMD. Follow-up analyses showed that LLLT significantly reduced pain at the short-term follow-up. Temporomandibular joint function outcomes indicated that the overall effect favored LLLT over placebo.
Conclusion
This systematic review suggests that LLLT effectively relieves pain and improves functional outcomes in patients with TMD.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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