Dangerous mistake: an accidental caffeine overdose
Andrade A, Sousa C, Pedro M, Fernandes M
BMJ case reports · 13 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Case report (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2018-06-08 · BMJ Case Rep · vol. 2018 · pp. bcr–2018
- Publisher
- BMJ
- Cited
- 30 citations · more than 82% of similar papers · 1.6× the field average
- References
- 13 works
- Access
- Open access (hybrid journal) · CC-BY-NC
- Research areas
- Coffee research and impacts · Pharmacology and Obesity Treatment · Cardiac pacing and defibrillation studies
- Keywords
- Medicine, Hypokalemia, Tachycardia, Caffeine, Anesthesia, Asymptomatic, Sinus tachycardia, Rhabdomyolysis, Metabolic acidosis, Emergency department, Internal medicine
- MeSH
- humans, psychomotor agitation, syncope, tachycardia, acidosis, hypokalemia, rare diseases, propranolol, caffeine, anti-arrhythmia agents, electrocardiography, treatment outcome, aftercare, dietary supplements, adult, female, administration, intravenous
4 authors
From PT
- Ana Carolina Porrio de Andrade · correspondingCentro De Medicina Veterinária Anjos De Assis
- Catarina SousaCentro De Medicina Veterinária Anjos De Assis
- Mónica Mendes PedroCentro De Medicina Veterinária Anjos De Assis
- Martinho FernandesCentro De Medicina Veterinária Anjos De Assis
Abstract
Caffeine (1,3,7-trimethylxanthine) is a natural product commonly presented in food's composition, beverages and medicinal products. Generally, it is thought to be safe under normal dosage, yet it can be fatal in case of severe intoxication. We report a case of a healthy 32-year-old woman who went to the local emergency department (ED) 30 min after ingesting, accidentally, 5000 mg of anhydrous caffeine for a preworkout supplement. At the ED, she presented an episode of presyncope followed by agitation. ECG showed polymorphic broad complex QRS tachycardia and arterial blood gas revealed metabolic acidaemia with severe hypokalemia. The dysrhythmia was successfully treated with intravenous propranolol. Acid-base and hydroelectrolytic disorders were also corrected. A persistent sinus tachycardia was observed in the first 2 days in the ward and 5 days later she was discharged asymptomatic with internal medicine follow-up.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC).
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