Photobiomodulation Therapy (PBMT) in Peripheral Nerve Regeneration: A Systematic Review
Rosso MPO, Buchaim DV, Kawano N, Furlanette G, Pomini KT, Buchaim RL
Bioengineering (Basel, Switzerland) · 78 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Systematic review (classified by our AI screen)
- Studied in
- People, plus animal or lab work
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2018-06-09 · Bioengineering (Basel) · vol. 5 · issue 2 · p. 44
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 125 citations · more than 87% of similar papers · 1.9× the field average
- References
- 55 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Laser Applications in Dentistry and Medicine · Electrospun Nanofibers in Biomedical Applications
- Keywords
- Regeneration (biology), Medicine, Peripheral, Peripheral nerve, Neuroscience, Anatomy, Biology, Internal medicine, Cell biology
6 authors
From BR
- Marcelie Priscila de Oliveira RossoUniversidade de São Paulo; Universidade Cidade de São Paulo
- Daniela Vieira BuchaimUniversidade de Marília; Solução Ambiental Assessoria e Consultoria; Centro Universitário Assunção; Centro Universitário de Adamantina
- Natália KawanoUniversidade de Marília
- Gabriela FurlanetteUniversidade de Marília
- Karina Torres PominiUniversidade de São Paulo; Universidade Cidade de São Paulo
- Rogério Leone Buchaim · correspondingUniversidade de São Paulo; Universidade Cidade de São Paulo; Universidade de Marília
Abstract
Photobiomodulation therapy (PBMT) has been investigated because of its intimate relationship with tissue recovery processes, such as on peripheral nerve damage. Based on the wide range of benefits that the PBMT has shown and its clinical relevance, the aim of this research was to carry out a systematic review of the last 10 years, ascertaining the influence of the PBMT in the regeneration of injured peripheral nerves. The search was performed in the PubMed/MEDLINE database with the combination of the keywords: low-level laser therapy AND nerve regeneration. Initially, 54 articles were obtained, 26 articles of which were chosen for the study according to the inclusion criteria. In the qualitative aspect, it was observed that PBMT was able to accelerate the process of nerve regeneration, presenting an increase in the number of myelinated fibers and a better lamellar organization of myelin sheath, besides improvement of electrophysiological function, immunoreactivity, high functionality rate, decrease of inflammation, pain, and the facilitation of neural regeneration, release of growth factors, increase of vascular network and collagen. It was concluded that PBMT has beneficial effects on the recovery of nerve lesions, especially when related to a faster regeneration and functional improvement, despite the variety of parameters.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.