Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study
Gabel K, Hoddy KK, Haggerty N, Song J, Kroeger CM, Trepanowski JF, Panda S, Varady KA
Nutrition and healthy aging · 445 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- National Institutes of Health
- University or hospital
- University of Illinois at Urbana-Champaign
- University or hospital
- University of Illinois at Chicago
- Authors
- At least one author declares a financial tie to industry
- Grants
- National Institutes of Health (R01HL106228); National Institutes of Health (T32-HL007909); National Institutes of Health (F32DK107157)
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2018-05-11 · Nutr Healthy Aging · vol. 4 · issue 4 · pp. 345–353
- Publisher
- IOS Press
- Cited
- 635 citations · more than 100% of similar papers · 32.7× the field average
- Impact
- Top 10% most cited in its field
- References
- 27 works
- Access
- Open access (hybrid journal) · CC-BY-NC
- Research areas
- Dietary Effects on Health · Circadian rhythm and melatonin · Sleep and related disorders
- Keywords
- Weight loss, Internal medicine, Medicine, Blood pressure, Endocrinology, Intermittent fasting, Obesity, Calorie, Calorie restriction, Cholesterol, Metabolic syndrome, Body weight
8 authors
From US
- Kelsey GabelUniversity of Illinois Chicago
- Kristin K. HoddyUniversity of Illinois Chicago
- Nicole HaggertyUniversity of Illinois Chicago
- Jeehee SongUniversity of Illinois Chicago
- Cynthia M. KroegerUniversity of Illinois Chicago; Indiana University Bloomington
- John F. TrepanowskiUniversity of Illinois Chicago
Abstract
Background
Time restricted feeding decreases energy intake without calorie counting and may be a viable option for weight loss. However, the effect of this diet on body weight in obese subjects has never been examined.
Objective
This study investigated the effects of 8-h time restricted feeding on body weight and metabolic disease risk factors in obese adults.
Design
Obese subjects (n = 23) participated in an 8-h time restricted feeding intervention (ad libitum feeding between 10:00 to 18:00 h, water fasting between 18:00 to 10:00 h) for 12 weeks. Weight loss and other outcomes were compared to a matched historical control group (n = 23).
Results
Body weight and energy intake decreased in the time restricted group (-2.6% ± 0.5; -341 ± 53 kcal/d) relative to controls over 12 weeks (P P < 0.05). Fat mass, lean mass, visceral fat mass, diastolic blood pressure, LDL cholesterol, HDL cholesterol, triglycerides, fasting glucose, fasting insulin, HOMA-IR, and homocysteine were not significantly different from controls after 12 weeks (no group×time interaction).
Conclusion
These findings suggest that 8-h time restricted feeding produces mild caloric restriction and weight loss, without calorie counting. It may also offer clinical benefits by reducing blood pressure.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC).
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