Meta-analysis2018

Association between obstructive sleep apnea and alcohol, caffeine and tobacco: A meta-analysis

Taveira KVM, Kuntze MM, Berretta F, de Souza BDM, Godolfim LR, Demathe T, De Luca Canto G, Porporatti AL

Journal of oral rehabilitation · 48 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Meta-analysis (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2018-07-04 · J Oral Rehabil · vol. 45 · issue 11 · pp. 890–902
Publisher
Wiley
Cited
67 citations · more than 90% of similar papers · 2.6× the field average
Impact
Top 10% most cited in its field
References
52 works
Access
Paywalled
Research areas
Obstructive Sleep Apnea Research · Neuroscience of respiration and sleep · Alcohol Consumption and Health Effects
Keywords
Meta-analysis, Medicine, Obstructive sleep apnea, Odds ratio, Confidence interval, Observational study, Scopus, CINAHL, MEDLINE, Internal medicine, Psychiatry, Psychological intervention
MeSH
humans, sleep apnea, obstructive, caffeine, odds ratio, alcohol drinking, tobacco use

8 authors

From BR

  • Karinna Veríssimo Meira Taveira · correspondingUniversidade Federal do Rio Grande do Norte
  • Morgane Marion KuntzeUniversidade Federal de Santa Catarina
  • Fernanda BerrettaUniversidade Federal de Santa Catarina
  • Beatriz Dulcinéia Mendes de SouzaUniversidade Federal de Santa Catarina
  • Luiz Roberto GodolfimUniversidade Federal de Santa Catarina
  • Thiago DematheUniversidade do Sul de Santa Catarina

Abstract

The aim of this systematic review was to answer the focused question, "Is there an association between obstructive sleep apnea (OSA) and alcohol, caffeine or tobacco use?" Five electronic databases (Cinahl, Literatura Latth American and Caribbean, PubMed, Scopus, Web of Science) and 3 grey literature (Google Acadêmico, ProQuest, OpenGrey) were searched, as well as search on reference list of included papers and contacts with study authors. Observational studies were included. The Meta-Analysis of Statistics Assessment and Review Instrument (MAStARI) tool assessed the potential risk of bias (RoB) among the studies, while the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach determined the level of evidence. Meta-Analysis was performed with RevMan 5.3 software. Among 3,442 identified studies, 14 were included. Eleven studies were classified as moderate RoB and 3 as high RoB. Meta-analysis showed OSA has no association with tobacco and presented a positive association with alcohol. The odds ratio for OSA increased almost 1.33 times (95% confidence interval [CI]; 1.10-1.62) for alcohol users. There was insufficient published data to evaluate whether OSA is associated with caffeine. The overall quality of evidence ranged from low to very low. OSA was associated with the use of alcohol, however there is not enough evidence to confirm the association with tobacco or caffeine. Due to the very low GRADE level of evidence, caution should be applied when considering these findings.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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