Nut consumption and risk of metabolic syndrome and overweight/obesity: a meta-analysis of prospective cohort studies and randomized trials
Li H, Li X, Yuan S, Jin Y, Lu J
Nutrition & metabolism · 52 citations
How it was studied
- Design
- Meta-analysis (classified by our AI screen)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2018-06-21 · Nutr Metab (Lond) · vol. 15 · issue 1 · p. 46
- Publisher
- BioMed Central
- Cited
- 65 citations · more than 82% of similar papers · 1.7× the field average
- References
- 101 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nuts composition and effects · Botany, Ecology, and Taxonomy Studies · Peanut Plant Research Studies
- Keywords
- Medicine, Overweight, Meta-analysis, Obesity, Prospective cohort study, Metabolic syndrome, Body mass index, Randomized controlled trial, Relative risk, Waist, Internal medicine, Confidence interval, Cohort study
5 authors
From CN
- Hang LiWuhan University; Zhongnan Hospital of Wuhan University
- Xia LiWuhan University; Zhongnan Hospital of Wuhan University
- Sheng YuanWuhan University; Zhongnan Hospital of Wuhan University
- Yalei JinWuhan University; Zhongnan Hospital of Wuhan University
- Jinping Lu · correspondingWuhan University; Zhongnan Hospital of Wuhan University
Abstract
Background
Nut consumption has been shown to reduce the risk of cardiovascular disease. However, its role in the prevention of metabolic disorders, such as metabolic syndrome (Mets) and overweight/obesity, remains controversial. We therefore conducted a meta-analysis to determine the association of nut consumption with Mets and overweight/obesity.
Methods
Eligible studies were identified by searching the PubMed and Embase databases and by reviewing the references of relevant literatures. We used random effect models to pool the studies-specific risk ratio (RR) and weighted mean difference (WMD).
Results
This meta-analysis included six prospective cohort studies with 420,890 subjects and 62 randomized feeding trials with 7184 participants. Among the cohort studies, the summary RR for every 1-serving/week increase in nut intake was 0.96 (95% confidence interval [CI]: 0.92 to 0.99; n = 3) for Mets, 0.97 (95% CI: 0.95 to 0.98; n = 2) for overweight/obesity, and 0.95 (95% CI: 0.89 to 1.02; n = 2) for obesity. Pooling of randomized trials indicated that nut consumption was related to a significant reduction in body weight (WMD: - 0.22 Kg, 95% CI: -0.40 to - 0.04), body mass index (WMD: - 0.16 Kg/m2, 95% CI: -0.31 to - 0.01), and waist circumference (WMD: - 0.51 cm, 95% CI: -0.95 to - 0.07). These findings remained stable in the sensitivity analysis, and no publication bias was detected.
Conclusion
Nut consumption may be beneficial in the prevention of Mets and overweight/obesity. Additional prospective studies are needed to enhance these findings and to explore the metabolic benefits for specific subclasses of nut.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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