Controlled clinical trial2018

The Improvement of Memory Deficits after Whole-Body Cryotherapy - The First Report

Rymaszewska J, Urbanska KM, Szczesniak D, Stanczykiewicz B, Trypka E, Zablocka A

Cryo letters · 13 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Controlled clinical trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2018-12-11 · Cryo Letters · vol. 39 · issue 3 · pp. 190–195
Publisher
National Institutes of Health
Cited
16 citations · more than 87% of similar papers · 2.1× the field average
References
0 works
Access
Paywalled
Research areas
Exercise and Physiological Responses · Therapeutic Uses of Natural Elements · Medical and Biological Ozone Research
Keywords
Medicine, Effects of sleep deprivation on cognitive performance, Cognition, Dementia, Internal medicine, Psychology, Psychiatry
MeSH
humans, cytokines, cryotherapy, aged, female, male, cold temperature, cognitive dysfunction

6 authors

From PL

  • Joanna RymaszewskaWroclaw Medical University
  • K M UrbanskaWroclaw Medical University
  • Dorota Maria SzcześniakWroclaw Medical University
  • Bartłomiej StańczykiewiczWroclaw Medical University
  • Elżbieta TrypkaWroclaw Medical University
  • Agnieszka ZabłockaLudwik Hirszfeld Institute of Immunology and Experimental Therapy

Abstract

Background

Mild Cognitive Impairments (MCI) and dementia are still incurable. The Whole-Body Cryotherapy (WBC) - short, cyclic exposure to extremely low temperatures - has proven anti-inflammatory and anti-oxidative effects. It can also induce hormonal, lipid and neural changes.

Objective

To evaluate the WBC effect on cognitive functioning and blood parameters of MCI patients.

Materials and methods

Participants with MCI undertook 10 WBC sessions. Cognitive functions and depressive symptoms were assessed before the first session, after the last session and 2 weeks later. Whole blood samples were collected.

Results

The cognitive functioning improved after 10 WBC sessions (p<0.05), especially memory processes. WBC caused a significant (p<0.05) increase of NO plasma level, BDNF concentration (p<0.05) and reduction of IL-6 (p<0.05). The moderate relationship between NO and cognitive functioning was noticed after WBC.

Conclusion

The preliminary results of the first study evaluating WBC on memory deficits suggest that WBC may be useful as a supportive therapy of MCI.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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