Molecular Mechanism and Health Role of Functional Ingredients in Blueberry for Chronic Disease in Human Beings
Ma L, Sun Z, Zeng Y, Luo M, Yang J
International journal of molecular sciences · 82 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Systematic review (classified by our AI screen)
- Main outcome
- Mechanisms only
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- the scientific research foundation of Yunnan Provincial Department of Education
- Government
- the Science and Technology to Benefit the People from Yunnan Provincial Scientific and Technology Department
- Government
- China Agriculture Research System
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2018-09-16 · Int J Mol Sci · vol. 19 · issue 9 · p. 2785
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 166 citations · more than 99% of similar papers · 6.9× the field average
- Impact
- Top 10% most cited in its field
- References
- 148 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Phytochemicals and Antioxidant Activities · Plant Gene Expression Analysis · Antioxidant Activity and Oxidative Stress
- Keywords
- Nutraceutical, Anthocyanidins, Polyphenol, Functional food, Medicine, Disease, Health benefits, Traditional medicine, Chronic disease, Mechanism (biology), Biology, Antioxidant, Biochemistry, Intensive care medicine
- MeSH
- animals, humans, chronic disease, plant extracts, dietary supplements, functional food, phytochemicals, blueberry plants
5 authors
From CN
- Luyao MaSouthwest Forestry University
- Zhenghai Sun · correspondingSouthwest Forestry University
- Yawen Zeng · correspondingYunnan Academy of Agricultural Sciences
- Mingcan LuoSouthwest Forestry University
- Jia-Zhen YangYunnan Academy of Agricultural Sciences
Abstract
Functional ingredients in blueberry have the best health benefits. To obtain a better understanding of the health role of blueberry in chronic disease, we conducted systematic preventive strategies for functional ingredients in blueberry, based on comprehensive databases, especially PubMed, ISI Web of Science, and CNKI for the period 2008⁻2018. Blueberry is rich in flavonoids (mainly anthocyanidins), polyphenols (procyanidin), phenolic acids, pyruvic acid, chlorogenic acid, and others, which have anticancer, anti-obesity, prevent degenerative diseases, anti-inflammation, protective properties for vision and liver, prevent heart diseases, antidiabetes, improve brain function, protective lung properties, strong bones, enhance immunity, prevent cardiovascular diseases, and improve cognitive decline. The anthocyanins and polyphenols in blueberry are major functional ingredients for preventive chronic disease. These results support findings that blueberry may be one of the best functional fruits, and further reveals the mechanisms of anthocyanins and polyphenols in the health role of blueberry for chronic disease. This paper may be used as scientific evidence for developing functional foods, nutraceuticals, and novel drugs of blueberry for preventive chronic diseases.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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