Comparative effects of different whole grains and brans on blood lipid: a network meta-analysis
Hui S, Liu K, Lang H, Liu Y, Wang X, Zhu X, Doucette S, Yi L, Mi M
European journal of nutrition · 34 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2018-09-22 · Eur J Nutr · vol. 58 · issue 7 · pp. 2779–2787
- Publisher
- Springer Science+Business Media
- Cited
- 45 citations · more than 87% of similar papers · 2.3× the field average
- References
- 44 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Food composition and properties · Food Science and Nutritional Studies · Wheat and Barley Genetics and Pathology
- Keywords
- Bran, Meta-analysis, Blood lipids, Cholesterol, Internal medicine, Medicine, Total cholesterol, Animal science, Food science, Chemistry, Biology
- MeSH
- humans, lipids, dietary fiber, whole grains
9 authors
From CN, CA
- Suocheng HuiArmy Medical University
- Kai LiuArmy Medical University; Shenyang Center for Disease Control and Prevention
- Hedong LangArmy Medical University
- Yang LiuArmy Medical University
- Xiaolan WangArmy Medical University
- Xiaohui ZhuArmy Medical University
Abstract
Purpose
The comparative effects of different whole grains and brans on blood lipid are still not totally elucidated. We aimed to estimate and rank the effects of different whole grains and brans on the control of blood lipid.
Methods
We performed a strategic literature search of PubMed, EMBASE and the Cochrane Library for relevant trials. Both pairwise meta-analyses and network meta-analyses were conducted to compare and rank the intervention strategies of whole grains and brans for the control of total cholesterol (TC), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), and triglycerides (TG).
Results
Fifty-five eligible trials with a total of 3900 participants were included. Cumulative ranking analyses showed that oat bran was the most effective intervention strategy for TC and LDL-C improvements, with significant decreases of - 0.35 mmol/L (95% CI - 0.47, - 0.23 mmol/L) and - 0.32 mmol/L (95% CI - 0.44, - 0.19 mmol/L) in TC and LDL-C compared with control, respectively. In comparison with control, oat was associated with significant reductions in TC by - 0.26 mmol/L (95% CI - 0.36, - 0.15 mmol/L) and LDL-C by - 0.17 mmol/L (95% CI - 0.28, - 0.07 mmol/L), which was ranked as the second best treatment. Barley, brown rice, wheat and wheat bran were shown to be ineffective in improving blood lipid compared with control.
Conclusions
This network meta-analysis suggests that oat bran and oat are ranked higher than any other treatments for the regulations of TC and LDL-C, indicating that increasing oat sources of whole grain may be recommended for lipid control.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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