Funded in part by Tecnología e Innovación Médico-Estética, S.L.
The effect of cryotherapy on fibromyalgia: a randomised clinical trial carried out in a cryosauna cabin
Rivera J, Tercero MJ, Salas JS, Gimeno JH, Alejo JS
Rheumatology international · 36 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Industry funded
- Company
- Tecnología e Innovación Médico-Estética, S.L.
- Authors
- At least one author declares a financial tie to industry
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2018-10-23 · Rheumatol Int · vol. 38 · issue 12 · pp. 2243–2250
- Publisher
- Springer Science+Business Media
- Cited
- 56 citations · more than 94% of similar papers · 3.7× the field average
- Impact
- Top 10% most cited in its field
- References
- 30 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Fibromyalgia and Chronic Fatigue Syndrome Research · Exercise and Physiological Responses · Occupational Health and Performance
- Keywords
- Medicine, Fibromyalgia, Visual analogue scale, Cryotherapy, Internal medicine, Crossover study, Physical therapy, Randomized controlled trial, Rheumatology, Surgery, Placebo
- MeSH
- humans, fibromyalgia, pain measurement, treatment outcome, cryotherapy, severity of illness index, cross-over studies, equipment design, time factors, adult, aged, aged, 80 and over, middle aged, spain, female, male, pain management, surveys and questionnaires
5 authors
From ES
- Javier Rivera · corresponding
- María José Tercero
- Javier Salas SalasPoliclínica Gipuzkoa
- Julio Hernández GimenoPoliclínica Gipuzkoa
- Javier Sánchez Alejo
Abstract
Evidence of symptomatic treatment for fibromyalgia (FM) is very low. Whole body cryotherapy (WBC) modulates different neurotransmitters, which might have a role in pain alleviation and could exert an effect on FM. Our aim was to evaluate the efficacy of WBC for the control of pain and impact of disease in FM. For this we run an open, randomized, crossover trial of Cryosense TCT™ cabin vs rest. Patients with FM according to ACR criteria were recruited consecutively from general practices. Trial endpoints were change (∆) in pain after 2 and 4 weeks, measured by a visual analogue scale (VAS), ∆ burden of disease, evaluated by the Fibromyalgia Impact Questionnaire (FIQ), and severity of FM, measured by the Combined Index of Severity of Fibromyalgia (ICAF). Within group differences, sequence and period effects were tested with Student's t or Mann-Whitney U tests. Multiple linear regression models were used to adjust effect by baseline differences between groups. Sixty patients were included in the trial. A period effect was noted, with residual effect of WBC; therefore, only results from the first sequence were analysed. ∆VAS pain, ∆FIQ and ∆ICAF scores were significantly larger in the WBC group after the first period (3.0 vs 0.3 in ∆VAS pain; 32.1 vs 0.4 in ∆FIQ; 13.7 vs 0.07 in ∆ICAF; all p < 0.001), and were confirmed after adjustment. In conclusion, WBC with a Cryosense TCT cabin may be a useful adjuvant therapy for FM; further studies on long-term effect and compared to other physical therapies are warranted.Trial registration NCT03425903.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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