Randomized controlled trial2018Open access

Effects of 4-Week Creatine Supplementation Combined with Complex Training on Muscle Damage and Sport Performance

Wang CC, Fang CC, Lee YH, Yang MT, Chan KH

Nutrients · 44 citations

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
Government
Ministry of Science and Technology, Taiwan
Grants
Ministry of Science and Technology, Taiwan (MOST 102-2410-H-179-002)

Based on 1 listed funder(s) and full-text disclosure statement.

Publication

Published
2018-11-02 · Nutrients · vol. 10 · issue 11 · p. 1640
Publisher
Multidisciplinary Digital Publishing Institute
Cited
83 citations · more than 89% of similar papers · 2.5× the field average
References
61 works
Access
Open access (journal) · CC-BY
Research areas
Muscle metabolism and nutrition · Sports Performance and Training · Exercise and Physiological Responses
Keywords
Creatine, Placebo, Creatine Monohydrate, Sprint, Creatine kinase, Medicine, Squat, Physical therapy, Strength training, Internal medicine, Muscle damage, Endocrinology
MeSH
muscle, skeletal, humans, creatine, exercise, drug administration schedule, double-blind method, body composition, sports, dietary supplements, adolescent, male, resistance training, young adult, athletes, performance-enhancing substances

5 authors

From TW

  • Chia‐Chi WangNational Taipei University of Business
  • Chu-Chun FangNational Taipei University of Business; National Taiwan Sport University
  • Ying-Hsian LeeNational Taiwan Sport University
  • Ming-Ta YangTaipei Medical University
  • Kuei‐Hui Chan · correspondingNational Taiwan Sport University

Abstract

Creatine supplementation has an ergogenic effect in an acute complex training bout, but the benefits of chronic creatine supplementation during long-term complex training remain unknown. The study aimed to evaluate the effects of 4-week complex training combined with creatine supplementation on sport performances and muscle damage biomarkers. Thirty explosive athletes were assigned to the creatine or placebo group, which consumed 20 g of creatine or carboxymethyl cellulose, respectively, per day for 6 days followed by 2 g of the supplements until the end of the study. After 6 days of supplementation, subjects performed tests of one repetition maximum (1-RM) strength of half squat and complex training bouts to determine the optimal individual post-activation potentiation time. Thereafter, all subjects performed a complex training programme consisting of six sets of 5-RM half squats and plyometric jumps 3 times per week for 4 weeks. Body composition, 30-m sprint and jump performances were assessed before and after the training period. Moreover, blood creatine kinase (CK) activity was analysed at the first and the last training bout. After the training, the 1-RM strength in the creatine group was significantly greater than in the placebo group (p p < 0.05). No differences were noted for other variables. This study concluded that creatine supplementation combined with complex training improved maximal muscular strength and reduced muscle damage during training.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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