25-Hydroxy cholecalciferol, anti-Müllerian hormone, and thyroid profiles among infertile men
Hassan MH, Ibrahim HM, El-Taieb MA
The aging male : the official journal of the International Society for the Study of the Aging Male · 8 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2018-11-22 · Aging Male · vol. 23 · issue 5 · pp. 513–519
- Publisher
- Informa
- Cited
- 13 citations · more than 86% of similar papers · 1.8× the field average
- References
- 51 works
- Access
- Free to read
- Research areas
- Ovarian function and disorders · Sexual Differentiation and Disorders · Hormonal and reproductive studies
- Keywords
- Medicine, Azoospermia, Internal medicine, Endocrinology, Testosterone (patch), Hormone, Prolactin, Infertility, Anti-Müllerian hormone, Thyroid function, Pregnancy, Biology
- MeSH
- thyroid gland, humans, cholecalciferol, follicle stimulating hormone, cross-sectional studies, male, anti-mullerian hormone
3 authors
From EG
- Mohammed H. Hassan · correspondingSouth Valley University
- Hassan M. IbrahimSouth Valley University
- Moustafa Adam El TaiebAswan University
Abstract
Background and aim
We examined the relationship among vit.D3, AMH, FT3, FT4, and TSH, in addition to the serum levels of reproductive hormones (FSH, LH, prolactin, and free testosterone), in oligoasthenoteratozoospermia and azoospermia patients in a cohort of infertile men from Egypt to establish a clinical marker/cause-effect relationship.
Methods
This cross-sectional cohort study was carried out on 301 men (105 males with oligoasthenoteratozoospermia and 96 males with azoospermia), in addition to 100 controls. Measurements of serum vit.D3, AMH, FT3, FT4, and TSH levels, in addition to reproductive hormone assays, were performed on all included subjects, using ELISA kits.
Results
Overall, results showed significantly lower serum levels of vit.D3 in infertile men than in the controls, with a greater decrease observed in men with azoospermia than in oligoasthenoteratozoospermia patients, (p p 3 levels (p < .05 for all).
Conclusion
Decreased Vit.D3 could play a role in male infertility, in addition to abnormal thyroid function, which needs further investigation.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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