The Effects of Oral Magnesium Supplementation on Glycemic Response among Type 2 Diabetes Patients
ELDerawi WA, Naser IA, Taleb MH, Abutair AS
Nutrients · 59 citations
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2018-12-26 · Nutrients · vol. 11 · issue 1 · p. 44
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 89 citations · more than 92% of similar papers · 3.0× the field average
- Impact
- Top 10% most cited in its field
- References
- 29 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Medicinal plant effects and applications
- Keywords
- Glycemic, Type 2 diabetes, Medicine, Diabetes mellitus, Magnesium, Internal medicine, Endocrinology, Gastroenterology, Chemistry
- MeSH
- humans, diabetes mellitus, type 2, insulin resistance, magnesium, blood glucose, administration, oral, dietary supplements, adult, middle aged, female, male
4 authors
From PS
- Wafaa A ELDerawiAl-Azhar University – Gaza
- Ihab Ali NaserAl-Azhar University – Gaza
- M. TalebAl-Azhar University – Gaza
- Ayman S. Abutair · correspondingAl-Azhar University – Gaza
Abstract
Background
Magnesium (Mg) supplementation may help control glycemic response among type 2 diabetes (T2D) patients.
Objective
This study means to determine whether Mg supplementation improves glycemic control indicators in patients with T2D.
Methods
After one week of the dietary stabilization phase, 42 T2D patients were stratified according to sex, age, fasting blood sugar (FBS) and Mg levels and then randomly allocated into two groups. The intervention group was on 250 mg/day of elemental Mg for three months while the control group did not receive any type of supplements throughout the intervention period.
Results
The daily administration of 250 mg of elemental Mg indicated a significant improvement in HbA1C (8.32 to 7.96%, p p p = 0.001), HOMA.IR (6.16 to 4.44, p p = 0.036) of the intervention group when compared with the control group after three months of intervention.
Conclusion
The results of this study revealed that oral Mg supplementation reduces insulin resistance and improves the glycemic control indicators among T2D patients.
Trial registration
current controlled trials PHRC/HC/32/15. Registered 5 October 2015.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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