Randomized controlled trial2019

Women Experience the Same Ergogenic Response to Caffeine as Men

Skinner TL, Desbrow B, Arapova J, Schaumberg MA, Osborne J, Grant GD, Anoopkumar-Dukie S, Leveritt MD

Medicine and science in sports and exercise · 53 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2019-01-15 · Med Sci Sports Exerc · vol. 51 · issue 6 · pp. 1195–1202
Publisher
Lippincott Williams & Wilkins
Cited
68 citations · more than 97% of similar papers · 6.2× the field average
Impact
Top 10% most cited in its field
References
36 works
Access
Paywalled
Research areas
Coffee research and impacts · Muscle metabolism and nutrition · Obesity, Physical Activity, Diet
Keywords
Caffeine, Psychology, Medicine, Physical therapy, Internal medicine
MeSH
humans, caffeine, central nervous system stimulants, body mass index, cross-over studies, double-blind method, sex factors, heart rate, physical endurance, bicycling, adult, female, male, young adult, performance-enhancing substances

8 authors

From AU, BE

  • Tina L. SkinnerThe University of Queensland; Nutrition Sciences (Belgium)
  • Ben DesbrowGriffith University
  • JULIA ARAPOVAThe University of Queensland; Nutrition Sciences (Belgium)
  • Mia Annalies SchaumbergThe University of Queensland; University of the Sunshine Coast; Nutrition Sciences (Belgium)
  • John Owen OsborneQueensland University of Technology; The University of Queensland; Nutrition Sciences (Belgium)
  • Gary Dean GrantGriffith University

Abstract

Purpose

This study aimed to determine whether 1) consumption of caffeine improves endurance cycling performance in women and 2) sex differences exist in the magnitude of the ergogenic and plasma responses to caffeine supplementation.

Methods

Twenty-seven (11 women and 16 men) endurance-trained cyclists and triathletes participated in this randomized, double-blind, placebo-controlled, crossover study. Participants completed an incremental exercise test to exhaustion, two familiarization trials, and two performance trials. Ninety minutes before the performance trials, participants ingested opaque capsules containing either 3 mg·kg body mass of anhydrous caffeine or a placebo. They then completed a set amount of work (75% of peak sustainable power output) in the fastest possible time. Plasma was sampled at baseline, preexercise, and postexercise for caffeine. Strict standardization and verification of diet, hydration, training volume and intensity, and contraceptive hormone phase (for women) were implemented.

Results

Performance time was significantly improved after caffeine administration in women (placebo: 3863 ± 419 s, caffeine: 3757 ± 312 s; P = 0.03) and men (placebo: 3903 ± 341 s, caffeine: 3734 ± 287 s; P < 0.001). The magnitude of performance improvement was similar for women (mean = 4.3%, 95% CI = 0.4%-8.2%) and men (4.6%, 2.3%-6.8%). Plasma caffeine concentrations were similar between sexes before exercise, but significantly greater in women after exercise (P < 0.001).

Conclusions

Ingestion of 3 mg·kg body mass of caffeine enhanced endurance exercise performance in women. The magnitude of the performance enhancement observed in women was similar to that of men, despite significantly greater plasma caffeine concentrations after exercise in women. These results suggest that the current recommendations for caffeine intake (i.e., 3-6 mg·kg caffeine before exercise to enhance endurance performance), which are derived almost exclusively from studies on men, may also be applicable to women.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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