Music Interventions in Pediatric Surgery (The Music Under Surgery In Children Study): A Randomized Clinical Trial
Kühlmann AYR, van Rosmalen J, Staals LM, Keyzer-Dekker CMG, Dogger J, de Leeuw TG, van der Toorn F, Jeekel J, Wijnen RMH, van Dijk M
Anesthesia and analgesia · 31 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2019-01-15 · Anesth Analg · vol. 130 · issue 4 · pp. 991–1001
- Publisher
- Lippincott Williams & Wilkins
- Cited
- 56 citations · more than 95% of similar papers · 5.3× the field average
- Impact
- Top 10% most cited in its field
- References
- 41 works
- Access
- Paywalled
- Research areas
- Music Therapy and Health · Pediatric Pain Management Techniques · Infant Development and Preterm Care
- Keywords
- Medicine, Randomized controlled trial, Anxiety, Perioperative, Psychological intervention, Interquartile range, Distress, Observational study, Music therapy, Physical therapy, FLACC scale, Anesthesia, Surgery, Internal medicine
- MeSH
- humans, treatment outcome, music therapy, intraoperative care, preoperative care, anesthesia, single-blind method, child behavior, anxiety, blood pressure, heart rate, child, preschool, infant, female, male, patient comfort
10 authors
From NL
- A. Y. Rosalie Kühlmann · correspondingErasmus MC
- Joost van RosmalenErasmus MC
- Lonneke M. Staals
- Claudia M. G. Keyzer‐Dekker · correspondingErasmus MC
- Jaap Dogger
- Thomas G. de Leeuw
Abstract
Background
Perioperative music interventions have been shown to reduce anxiety and pain in adults. This inexpensive, easily applicable intervention could be of benefit to children as well. Our objective was to determine the effects of music interventions on distress, anxiety, and postoperative pain in infants undergoing surgery.
Methods
The Music Under Surgery In Children study was designed as a parallel, single-blind, randomized controlled trial with an a priori formulated hypothesis. Data were collected between August 2015 and October 2016 in a single tertiary care children's hospital. There was a 24-hour follow-up with blind primary outcome assessment. A random sample of 432 eligible 0-3 years of age infants admitted for orchidopexy, hypospadias, or inguinal hernia repair receiving general anesthesia and caudal block were asked for participation. Subjects were assigned to a preoperative music intervention, pre- and intraoperative music intervention, or no music intervention (control) via random allocation using a computer-generated list with the use of opaque envelopes. The main outcome measure was the postoperative level of distress assessed with the COMFORT-Behavior scale, which is an observational scale; furthermore, preoperative level of distress, preoperative anxiety, and physiological measurements such as heart rate (HR) and blood pressure were measured. The trial was registered at the Dutch Trial Register, number NTR5402 (www.trialregister.nl).
Results
One hundred ninety-five infants with median age 6.9 months (interquartile range, 3.3-11.1) were randomized, 178 of whom were included in the primary analysis. A nonsignificant difference in COMFORT-Behavior scale scores between the pre- and intraoperative music intervention group and control group at 4 hours after surgery was found (mean difference, -1.22; 95% CI, 2.60-0.17; P = .085). Additional analysis showed weak nonsignificant evidence for an interaction effect between music exposure and COMFORT-Behavior score at baseline (P = .027 with a Bonferroni-adjusted significance level of .025). General linear modeling showed a statistically significantly reduced HR after the preoperative music intervention in the holding area in the combined preoperative music intervention and intraoperative music intervention group compared to the control group (P = .003). The differences in HR among the 3 study arms at all time points were not statistically significant (P = .069).
Conclusions
Music interventions do not seem to benefit all young infants undergoing surgery. The potential benefits of music interventions in the preoperative period and in more distressed children warrant further exploration.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.