Red meat and processed meat intake and risk of colorectal cancer: a population-based case-control study
Saliba W, Rennert HS, Gronich N, Gruber SB, Rennert G
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 18 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- Government
- National Cancer Institute
- Government
- NCI NIH HHS
- Grants
- National Cancer Institute (R01CA197350); National Cancer Institute (R01 CA081488)
Based on 2 listed funder(s).
Publication
- Published
- 2019-01-25 · Eur J Cancer Prev · vol. 28 · issue 4 · pp. 287–293
- Publisher
- Lippincott Williams & Wilkins
- Cited
- 28 citations · more than 66% of similar papers · 0.9× the field average
- References
- 20 works
- Access
- Open access (repository copy)
- Research areas
- Cancer, Lipids, and Metabolism · Colorectal Cancer Screening and Detection · Nutritional Studies and Diet
- Keywords
- Red meat, Medicine, Odds ratio, White meat, Colorectal cancer, Confidence interval, Processed meat, Mediterranean diet, Population, Epidemiology, Environmental health, Food science, Cancer, Internal medicine, Biology
- MeSH
- animals, cattle, sheep, swine, humans, colorectal neoplasms, diet surveys, incidence, odds ratio, risk factors, case-control studies, prospective studies, feeding behavior, adult, middle aged, israel, female, male, red meat
5 authors
From IL, US
- Walid Saliba · correspondingTechnion – Israel Institute of Technology; Carmel Medical Center; Clalit Health Services
- Hedy S. RennertTechnion – Israel Institute of Technology; Carmel Medical Center; Clalit Health Services
- Naomi GronichTechnion – Israel Institute of Technology; Carmel Medical Center; Clalit Health Services
- Stephen B. GruberUniversity of Southern California
- Gad RennertTechnion – Israel Institute of Technology; Carmel Medical Center; Clalit Health Services
Abstract
To examine the association between red meat subtypes intake and risk of colorectal cancer (CRC) among Jewish and Arabs populations in a unique Mediterranean environment. The Molecular Epidemiology of Colorectal Cancer study (n=10 026) is a prospective population-based case-control study in northern Israel. Participants were interviewed in-person about their dietary intake and lifestyle using a questionnaire that included a food-frequency questionnaire. Red meat consumption in Israel was found to be especially low in the Jewish population (1.29±1.45 servings/week), but higher in Arabs (3.0±1.98 servings/week) (P<0.001). Beef was the most commonly consumed red meat by Jews (1.15/1.29 servings/week, 89%) and proportionally less so by Arabs (2.00/3.00, 67%). Processed meat consumption (mostly pork free) was lower among Arabs (0.9±1.56 servings/week) compared with Jews (1.97±2.97 servings/week) (P<0.001). The adjusted odds of CRC per one serving/week of red meat were 1.05 (95% confidence interval: 1.01-1.08) in Jews and 0.94 (0.88-1.01) in Arabs. Compared with no consumption, beef consumption was associated with odds ratio (OR)=0.96 (0.86-1.07) in Jews and 0.94 (0.61-1.45) in Arabs, lamb consumption with OR=1.28 (1.10-1.5) and 1.01 (0.75-1.37), pork consumption with OR=1.44 (1.24-1.67) and 1.07 (0.73-1.56), and processed meat consumption with OR=1.22 (1.10-1.35) and 1.04 (0.82-1.33) in Jews and Arabs, respectively. Overall red meat consumption was associated weakly with CRC risk, significant only for lamb and pork, but not for beef, irrespective of tumor location. Processed meat was associated with mild CRC risk.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.