Wake up and smell the coffee: caffeine supplementation and exercise performance-an umbrella review of 21 published meta-analyses
Grgic J, Grgic I, Pickering C, Schoenfeld BJ, Bishop DJ, Pedisic Z
British journal of sports medicine · 239 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2019-03-29 · Br J Sports Med · vol. 54 · issue 11 · pp. 681–688
- Publisher
- BMJ
- Cited
- 368 citations · more than 100% of similar papers · 30.3× the field average
- Impact
- Top 10% most cited in its field
- References
- 64 works
- Access
- Free to read
- Research areas
- Coffee research and impacts · Muscle metabolism and nutrition · Pharmacology and Obesity Treatment
- Keywords
- Caffeine, Medicine, Anaerobic exercise, Meta-analysis, Physical therapy, Checklist, Aerobic exercise, Systematic review, Jumping, Physical medicine and rehabilitation, Quality of evidence, MEDLINE, Physiology, Internal medicine, Psychology
- MeSH
- muscle, skeletal, humans, caffeine, exercise, sex factors, coffee, dietary supplements, female, male, muscle strength, athletic performance, performance-enhancing substances
6 authors
From AU, DE, GB, US
- Jozo Grgić · correspondingVictoria University
- Ivana GrgicGollwitzer-Meier-Klinik
- Craig PickeringUniversity of Lancashire; Genomics England
- Brad Jon SchoenfeldLehman College
- David John BishopEdith Cowan University; Victoria University
- Željko PedišićVictoria University
Abstract
Objective
To systematically review, summarise and appraise findings of published meta-analyses that examined the effects of caffeine on exercise performance.
Design
Umbrella review.
Data sources
Twelve databases.
Eligibility criteria for selecting studies
Meta-analyses that examined the effects of caffeine ingestion on exercise performance.
Results
Eleven reviews (with a total of 21 meta-analyses) were included, all being of moderate or high methodological quality (assessed using the Assessing the Methodological Quality of Systematic Reviews 2 checklist). In the meta-analyses, caffeine was ergogenic for aerobic endurance, muscle strength, muscle endurance, power, jumping performance and exercise speed. However, not all analyses provided a definite direction for the effect of caffeine when considering the 95% prediction interval. Using the Grading of Recommendations Assessment, Development and Evaluation criteria the quality of evidence was generally categorised as moderate (with some low to very low quality of evidence). Most individual studies included in the published meta-analyses were conducted among young men.
Summary/conclusion
Synthesis of the currently available meta-analyses suggest that caffeine ingestion improves exercise performance in a broad range of exercise tasks. Ergogenic effects of caffeine on muscle endurance, muscle strength, anaerobic power and aerobic endurance were substantiated by moderate quality of evidence coming from moderate-to-high quality systematic reviews. For other outcomes, we found moderate quality reviews that presented evidence of very low or low quality. It seems that the magnitude of the effect of caffeine is generally greater for aerobic as compared with anaerobic exercise. More primary studies should be conducted among women, middle-aged and older adults to improve the generalisability of these findings.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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