Associations between higher egg consumption during pregnancy with lowered risks of high blood pressure and gestational diabetes mellitus
Milajerdi A, Tehrani H, Haghighatdoost F, Larijani B, Surkan PJ, Azadbakht L
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 14 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Case-control study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2018-06-01 · Int J Vitam Nutr Res · vol. 88 · issue 3-4 · pp. 166–175
- Publisher
- Hogrefe Verlag
- Cited
- 17 citations · more than 80% of similar papers · 1.1× the field average
- References
- 37 works
- Access
- Paywalled
- Research areas
- Gestational Diabetes Research and Management · Birth, Development, and Health · Diet and metabolism studies
- Keywords
- Gestational diabetes, Medicine, Odds ratio, Confidence interval, Pregnancy, Cholesterol, Diabetes mellitus, Blood pressure, Logistic regression, Obstetrics, Odds, Internal medicine, Endocrinology, Gestation, Biology
- MeSH
- ovum, humans, diabetes, gestational, hypertension, risk factors, case-control studies, pregnancy, child, iran, female
6 authors
From IR
- Alireza MilajerdiTehran University of Medical Sciences
- Hatav Ghasemi TehraniIsfahan University of Medical Sciences
- Fahimeh HaghighatdoostIsfahan University of Medical Sciences
- Bagher A. LarijaniTehran University of Medical Sciences
- Pamela Jean Surkan
- Leila AzadbakhtIsfahan University of Medical Sciences; Endocrinology and Metabolism Clinical Sciences Institute; Tehran University of Medical Sciences
Abstract
Introduction: The prevalence of gestational diabetes mellitus (GDM) is increasing worldwide. High cholesterol intake may increase the risk of hyperglycemia, yet little research has evaluated the relation between cholesterol or egg as a main source of dietary cholesterol and GDM. We aimed to study this association among pregnant Iranian women. Methods and Participants: Four hundred sixty-two pregnant women participated in this case-control study. Participants' dietary intake, weight, height, and blood pressure were obtained and BMI was calculated. Fasting plasma glucose and liver enzymes were also measured. Logistic regression was used to obtain odds ratios and 95% confidence intervals for GDM across tertiles of cholesterol and egg consumption. Results: Among study participants, 115 consumed less than one, 194 consumed one and the remaining participants consumed more than one egg per week (mean cholesterol intake 121.31±61.69 mg/d). Participants within the highest tertile of egg consumption had 41% lower risk of GDM (OR: 0.59; 95% CI: 0.35-0.99) compared with those in the lowest tertile (P=0.01). Higher egg consumption was associated with lower risk of having high blood pressure (P=0.01). The difference in odds of GDM and high blood pressure between the highest and the lowest tertile of cholesterol consumption was not significant, even after controlling for age, energy intake, number of children and socio-economic status. Conclusion: Higher dietary intake of egg during pregnancy was associated with lower odds of GDM. We found no significant association between cholesterol intake and odds of GDM. Further research are needed to confirm these results and determine causality.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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