Systematic review2019Industry funded

Funded in part by Wild Blueberry Association of North America

Systematic Review of the Effects of Blueberry on Cognitive Performance as We Age

Hein S, Whyte AR, Wood E, Rodriguez-Mateos A, Williams CM

The journals of gerontology. Series A, Biological sciences and medical sciences · 45 citations

Review labels

Industry funded

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Systematic review (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Not stated

Who paid for it

Funding
Industry funded
Industry group
Wild Blueberry Association of North America

Based on 1 listed funder(s).

Publication

Published
2019-04-02 · J Gerontol A Biol Sci Med Sci · vol. 74 · issue 7 · pp. 984–995
Publisher
Oxford University Press
Cited
63 citations · more than 87% of similar papers · 2.3× the field average
References
53 works
Access
Open access (repository copy)
Research areas
Medicinal Plants and Neuroprotection · Antioxidant Activity and Oxidative Stress · Neurological Disease Mechanisms and Treatments
Keywords
Cognition, Biology, Psychology, Neuroscience
MeSH
humans, plants, medicinal, flavonoids, cognition, aging, executive function, repression, psychology, blueberry plants

5 authors

From GB

  • Sabine HeinKing's College London; University of Reading
  • Adrian Robert WhyteUniversity of Reading
  • Eleanor WoodKing's College London; University of Reading
  • Ana Rodriguez‐MateosKing's College London
  • Claire Michelle Williams · correspondingUniversity of Reading

Abstract

The effect of flavonoid-rich food, such as blueberries, on cognitive function has been subject to a growing amount of research interest in recent years. Epidemiological, prospective, preclinical, and clinical trials have revealed positive cognitive benefits from flavonoid interventions, particularly in relation to the amelioration of cognitive decline in older adults. This review will specifically consider the existing clinical research from both acute and chronic blueberry interventions on cognition in human subjects. The results of 11 studies are reported with 4 studies considering blueberry intervention with children aged 7-10 years, 4 considering adults aged 60 years and older, and 3 considering adults suffering from mild cognitive impairment (MCI). Findings from these studies indicate that cognitive benefits may be found for delayed memory and executive function in children and for delayed memory, executive function, and psychomotor function in older healthy and MCI adults. There is less evidence to suggest positive benefits of blueberry intervention on working memory. Recommendations for future research, including dose used, cognitive tasks, and age groups considered, are proposed.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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