Association between Dietary Cholesterol and Their Food Sources and Risk for Hypercholesterolemia: The 2012⁻2016 Korea National Health and Nutrition Examination Survey
Cha D, Park Y
Nutrients · 16 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- National Research Foundation of Korea grant
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2019-04-15 · Nutrients · vol. 11 · issue 4 · p. 846
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 41 citations · more than 95% of similar papers · 4.9× the field average
- Impact
- Top 10% most cited in its field
- References
- 50 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Fatty Acid Research and Health
- Keywords
- National Health and Nutrition Examination Survey, Cholesterol, Odds ratio, Medicine, Dietary Cholesterol, Confidence interval, Internal medicine, Ldl cholesterol, Endocrinology, Saturated fat, Environmental health, Population
- MeSH
- humans, hypercholesterolemia, cholesterol, dietary, fatty acids, diet, nutrition surveys, odds ratio, feeding behavior, energy intake, meat, adult, middle aged, female, male, cholesterol, ldl, republic of korea
2 authors
From KR
- Dongjoo ChaHanyang University; Anyang University
- Yongsoon Park · correspondingHanyang University; Anyang University
Abstract
It remains unclear whether cholesterol intake can increase serum cholesterol. Therefore, the present study aimed to investigate the hypothesis that the risk for hypercholesterolemia was not associated with intake of dietary cholesterol after adjusting for saturated fatty acid (SFA). Based on the data from the 2012-2016 KNHANES, dietary cholesterol was positively associated with the risk for abnormalities in total cholesterol (TC) (odds ratio (OR): 1.153, 95% confidence interval (CI): 0.995-1.337; p = 0.028) and low-density lipoprotein cholesterol (LDL-C) (OR: 1.186, 95% CI: 1.019-1.382; p = 0.018) levels before adjusting for SFA; after adjusting for SFA, no significant associations were found between these variables. The mediation analysis showed that dietary cholesterol had no direct effects on the serum levels of TC and LDL-C; in contrast, SFA had significant indirect effects on the association between dietary cholesterol and serum levels of TC and LDL-C. Furthermore, processed meats, but not eggs and other meats, were positively associated with the risk for abnormalities in both TC (OR: 1.220, 95% CI: 1.083-1.374; p = 0.001) and LDL-C (OR: 1.193, 95% CI: 1.052-1.354; p = 0.004) levels. The present study suggested that higher intake of processed meats with high SFA, but not dietary cholesterol was associated with higher risk for abnormalities in TC and LDL-C levels.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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