The effect of age, gender, and sexual maturation on the caffeine breath test
Lambert GH, Schoeller DA, Kotake AN, Flores C, Hay D
Developmental pharmacology and therapeutics · 52 citations
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- National Institutes of Health
- Government
- National Institute of General Medical Sciences
- Government
- NIGMS NIH HHS
- Government
- NIADDK NIH HHS
- Grants
- National Institutes of Health (2p30am026678-06); National Institute of General Medical Sciences (5-T32); National Institute of General Medical Sciences (GM-07019)
Based on 4 listed funder(s).
Publication
- Published
- 2017-08-11 · Dev Pharmacol Ther · vol. 9 · issue 6 · pp. 375–388
- Publisher
- Karger Publishers
- Cited
- 88 citations · more than 57% of similar papers · 0.4× the field average
- References
- 0 works
- Access
- Paywalled
- Research areas
- Advanced Chemical Sensor Technologies · Coffee research and impacts · Biochemical Analysis and Sensing Techniques
- Keywords
- Caffeine, Exhalation, Young adult, Sexual maturity, Medicine, Internal medicine, Breath test, Psychology, Sex characteristics, Physiology, Endocrinology, Anesthesia
- MeSH
- humans, carbon dioxide, caffeine, cytochrome p-450 enzyme system, breath tests, age factors, sex factors, aging, sexual maturation, adolescent, adult, child, child, preschool, female, male
5 authors
From US
- George H. LambertLoyola University Chicago; University of Chicago
- Dale A. SchoellerLoyola University Chicago; University of Chicago
- Alvin N. KotakeLoyola University Chicago; University of Chicago
- Carlos FloresLoyola University Chicago; University of Chicago
- Deborah Hay
Abstract
This study demonstrated the feasibility of utilizing the (3-13C-methyl) caffeine breath test (CBT) in children and adolescents, and examined the effect of gender, age, and puberty on the CBT. The CBT, expressed as the 2-hour accumulative exhalation of labeled CO2 (2-hour CO2), was compared to the CBT results in the adult. The 2-hour CO2 values were higher in the children than the adult, and the decrease in the CO2 values occurred in males during late puberty and in females during early puberty.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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