Cruciferous Vegetable Consumption and Stomach Cancer: A Case-Control Study
Morrison MEW, Joseph JM, McCann SE, Tang L, Almohanna HM, Moysich KB
Nutrition and cancer · 7 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- Government
- National Cancer Institute
- Government
- National Cancer Institute of the National Institutes of Health
- University or hospital
- Roswell Park Cancer Institute and National Cancer Institute
- Government
- NCI NIH HHS
- Grants
- National Cancer Institute (R25CA181003); National Cancer Institute (#P30 CA016056)
Based on 4 listed funder(s).
Publication
- Published
- 2019-05-16 · Nutr Cancer · vol. 72 · issue 1 · pp. 52–61
- Publisher
- Routledge
- Cited
- 18 citations · more than 87% of similar papers · 2.1× the field average
- References
- 38 works
- Access
- Open access (repository copy)
- Research areas
- Helicobacter pylori-related gastroenterology studies · Genomics, phytochemicals, and oxidative stress · Ovarian cancer diagnosis and treatment
- Keywords
- Cruciferous vegetables, Stomach cancer, Medicine, Odds ratio, Cancer, Confounding, Stomach, Logistic regression, Confidence interval, Case-control study, Epidemiology, Internal medicine
- MeSH
- humans, vegetables, stomach neoplasms, diet, risk factors, case-control studies, cohort studies, middle aged, female, male, raw foods, surveys and questionnaires
6 authors
From US
- Maia E. W. MorrisonUniversity at Buffalo, State University of New York
- Janine M. JosephRoswell Park Comprehensive Cancer Center
- Susan E. McCannRoswell Park Comprehensive Cancer Center
- Li TangRoswell Park Comprehensive Cancer Center
- Hani AlmohannaRoswell Park Comprehensive Cancer Center
- Kirsten B. Moysich · correspondingRoswell Park Comprehensive Cancer Center
Abstract
Objective: To investigate the association between regular cruciferous vegetable intake and stomach cancer.Methods: A hospital-based, case-control study was conducted at Roswell Park Comprehensive Cancer Center in Buffalo, NY, which included 292 stomach cancer patients and 1168 cancer-free controls recruited between 1992 and 1998 as part of the Patient Epidemiology Data System (PEDS). Dietary and other epidemiologic and confounding variables were collected by questionnaire. Multivariable logistic regression analyses were utilized to estimate odds ratios (OR) and 95% confidence intervals (CI) for associations between usual pre-diagnostic cruciferous vegetable intake and stomach cancer, with adjustment for other stomach cancer risk factors and dietary characteristics.Results: We observed strong inverse associations between stomach cancer and highest versus lowest intakes of total cruciferous vegetables (OR = 0.59, 95% CI: 0.42-0.83), raw cruciferous vegetables (OR = 0.53, 95% CI: 0.38-0.73), raw broccoli (OR = 0.61, 95% CI: 0.43-0.86), raw cauliflower (OR = 0.51, 95% CI: 0.35-0.73), and Brussels sprouts (OR = 0.66, 95% CI = 0.48-0.91).Conclusions: These data suggest that consuming raw cruciferous vegetables may be associated with a lower odds of stomach cancer, even after considering other dietary characteristics.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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