Proteomics Analysis of Urine to Examine Physical Effects of Warm Nano Mist Sauna Bathing
Hirao Y, Kinoshita N, Xu B, Saito S, Quadery AF, Elguoshy A, Yamamoto K, Yamamoto T
Healthcare (Basel, Switzerland) · 2 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Independent funding
- Government
- Ministry of Education, Culture, Sports, Science and Technology
- Unclassified
- Center of Innovation Program
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2019-05-19 · Healthcare (Basel) · vol. 7 · issue 2 · p. 71
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 2 citations · more than 5% of similar papers · 0.0× the field average
- References
- 20 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Muscle metabolism and nutrition · Thermoregulation and physiological responses · Skin Protection and Aging
- Keywords
- Mist, Urine, Bathing, Medicine, Chemistry, Internal medicine, Pathology
8 authors
From JP
- Yoshitoshi HiraoNiigata University
- Naohiko KinoshitaNiigata University of Health and Welfare; Niigata University
- Bo XuNiigata University
- Suguru SaitoNiigata University
- Ali F. QuaderyNiigata University
- Amr ElguoshyNiigata University
Abstract
Conventional sauna bathing may have some health benefits as it facilitates relaxing, detoxing and promoting metabolism. However, conventional sauna bathing at a high temperature may be harmful for the body by increasing the risk of heart failure. The nano-mist sauna has been developed to provide nano-size water particles at a lower temperature. Hence, nano-mist sauna bathing is expected to be useful for health without the risks that arise at high temperatures. In this study, we performed a comprehensive proteomics analysis of urine samples obtained from healthy volunteers before and after they had taken a sauna bath with nano-mist (n = 10) or with conventional mist (n = 10) daily for two weeks (4 groups). The average numbers of urine proteins identified by liquid chromatography-linked mass chromatography in each group varied from 678 to 753. Interestingly, the protein number was increased after sauna bathing both with nano-mist or with conventional mist. Quantitative analysis indicated that considerable numbers of proteins were obviously up-regulated, with more than two-folds in urine samples after the nano-mist sauna bathing. The KEGG pathway analysis showed significant stimulation of the lysosome pathway (p = 5.89E-6) after the nano-mist bathing, which may indicate the nano-mist sauna bathing promotes metabolism related to the lysosome pathway more efficiently than conventional mist sauna bathing and may provide more health benefits.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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