Study2019Open access

Impact of olive oil and honey on healing of diabetic foot: a randomized controlled trial

Karimi Z, Behnammoghadam M, Rafiei H, Abdi N, Zoladl M, Talebianpoor MS, Arya A, Khastavaneh M

Clinical, cosmetic and investigational dermatology · 27 citations

How it was studied

Design
Randomized controlled trial (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding

Based on full-text disclosure statement.

Publication

Published
2019-05-01 · Clin Cosmet Investig Dermatol · vol. Volume 12 · pp. 347–354
Publisher
Dove Medical Press
Cited
47 citations · more than 93% of similar papers · 4.0× the field average
Impact
Top 10% most cited in its field
References
21 works
Access
Open access (journal) · CC-BY-NC
Research areas
Bee Products Chemical Analysis · Diabetic Foot Ulcer Assessment and Management · Nuts composition and effects
Keywords
Diabetic foot, Olive oil, Medicine, Randomized controlled trial, Foot (prosody), Diabetes mellitus, Internal medicine, Traditional medicine, Food science, Endocrinology, Chemistry, Art

8 authors

From IR

  • Zohreh KarimiYasuj University of Medical Sciences
  • Mohammad BehnammoghadamYasuj University of Medical Sciences
  • Hossein RafieiQazvin University of Medical Sciences
  • Naeem AbdiYasuj University of Medical Sciences
  • Mohammad ZoladlYasuj University of Medical Sciences
  • Mohammad Sharif TalebianpoorYasuj University of Medical Sciences

Abstract

Background: This study aimed 1) to examine the impact of honey on diabetic foot; 2) to examine the effect of olive oil on diabetic foot; and 3) to compare the impact of honey and olive oil in the healing of diabetic foot. Methods: In this randomized controlled trial, 45 patients took part. Patients were randomly assigned to three groups. In the honey group, the wound was dressed using gauzes with honey daily for 1 month. In the olive oil group, the wound was dressed using gauzes with olive oil (4 mL) daily for 1 month. Patients in the control group received usual dressing. Wounds were assessed before and after intervention using the Wagner scoring system and the checklist of diabetic foot healing (where a higher score indicates better wound healing). Results: Demographic characteristics of patients in the three groups were similar. Mean scores of tissue around the wound, wound grade, wound drainage, and wound healing were similar before intervention in all three groups. After intervention, means score of tissue around the wound, wound grade, wound drainage, and wound healing were significantly higher in patients in the honey and olive oil groups compared to patients in the control group. Conclusion: The results of this study reveal that honey is as effective as olive oil in the treatment of diabetic foot. Given the few studies on this topic, further investigation is needed.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC).

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