Funded in part by International Nut and Dried Fruit Council, International Nut and Dried Fruit Council (INC)
Effect of Nut Consumption on Erectile and Sexual Function in Healthy Males: A Secondary Outcome Analysis of the FERTINUTS Randomized Controlled Trial
Salas-Huetos A, Muralidharan J, Galiè S, Salas-Salvadó J, Bulló M
Nutrients · 12 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food provided by researchers
Who paid for it
- Funding
- Industry funded
- University or hospital
- Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición
- Industry group
- International Nut and Dried Fruit Council
- Government
- National Institutes of Health
- Government
- Instituto de Salud Carlos III
- Industry group
- International Nut and Dried Fruit Council (INC)
- Authors
- At least one author declares a financial tie to industry
Based on 5 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2019-06-19 · Nutrients · vol. 11 · issue 6 · p. 1372
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 22 citations · more than 87% of similar papers · 2.3× the field average
- References
- 36 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nuts composition and effects · Hormonal and reproductive studies · Phytoestrogen effects and research
- Keywords
- Nut, Erectile function, Randomized controlled trial, Medicine, Outcome (game theory), Sexual function, Erectile dysfunction, Consumption (sociology), Internal medicine, Demography
- MeSH
- humans, nuts, nitric oxide, e-selectin, sexual behavior, nutritive value, penile erection, time factors, adolescent, adult, spain, male, young adult, healthy volunteers, recommended dietary allowances, diet, western, biomarkers, diet, healthy
5 authors
From ES
- Albert Salas‐HuetosInstituto de Salud Carlos III; Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition; Institut de Recerca Biomèdica Catalunya Sud; Universitat Rovira i Virgili
- Jananee MuralidharanInstitut de Recerca Biomèdica Catalunya Sud; Universitat Rovira i Virgili
- Serena GaliéInstitut de Recerca Biomèdica Catalunya Sud; Universitat Rovira i Virgili
- Jordi Salas‐Salvadó · correspondingInstituto de Salud Carlos III; Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition; Institut de Recerca Biomèdica Catalunya Sud; Hospital Universitari Sant Joan de Reus; Universitat Rovira i Virgili
- Mònica Bulló · correspondingInstituto de Salud Carlos III; Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition; Institut de Recerca Biomèdica Catalunya Sud; Universitat Rovira i Virgili
Abstract
Lifestyle risk factors for erectile and sexual function include smoking, excessive alcohol consumption, lack of physical activity, psychological stress, and adherence to unhealthy diets. In the present study, we evaluated the effects of mixed nuts supplementation on erectile and sexual function. Eighty-three healthy male aged 18-35 with erectile function assessment were included in this FERTINUTS study sub-analysis; a 14-week randomized, controlled, parallel feeding trial. Participants were allocated to (1) the usual Western-style diet enriched with 60 g/day of a mixture of nuts (nut group; n = 43), or (2) the usual Western-style diet avoiding nuts (control group; n = 40). At baseline and the end of the intervention, participants answered 15 questions contained in the validated International Index of Erectile Function (IIEF), and peripheral levels of nitric oxide (NO) and E-selectin were measured, as surrogated markers of erectile endothelial function. Anthropometrical characteristics, and seminogram and blood biochemical parameters did not differ between intervention groups at baseline. Compared to the control group, a significant increase in the orgasmic function (p-value = 0.037) and sexual desire (p-value = 0.040) was observed during the nut intervention. No significant differences in changes between groups were shown in peripheral concentrations of NO and E-selectin. Including nuts in a regular diet significantly improved auto-reported orgasmic function and sexual desire.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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