Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults
Abbaspour N, Roberts T, Hooshmand S, Kern M, Hong MY
Nutrients · 26 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food provided by researchers
Who paid for it
- Funding
- Independent funding
- Nonprofit
- American Heart Association
- Grants
- American Heart Association (16GRNT31360007)
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2019-06-29 · Nutrients · vol. 11 · issue 7 · p. 1488
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 42 citations · more than 93% of similar papers · 3.6× the field average
- Impact
- Top 10% most cited in its field
- References
- 59 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nuts composition and effects · Antioxidant Activity and Oxidative Stress · Nutritional Studies and Diet
- Keywords
- Overweight, Nut, Medicine, Obesity, Diabetes mellitus, Randomized controlled trial, Internal medicine, Endocrinology
- MeSH
- humans, nuts, cardiovascular diseases, obesity, weight loss, insulin, l-lactate dehydrogenase, blood glucose, lipids, body mass index, treatment outcome, risk factors, time factors, adolescent, adult, middle aged, female, male, young adult, snacks, biomarkers
5 authors
From US
- Nazanin AbbaspourSan Diego State University
- Traci RobertsSan Diego State University
- Shirin HooshmandSan Diego State University
- Mark KernSan Diego State University
- Mee Young Hong · correspondingSan Diego State University
Abstract
Emerging research indicates that nuts are a source of health-promoting compounds demonstrating cardioprotective benefits. However, most studies have assessed the effect of single nuts rather than a nut mixture. The objective of this study was, therefore, to examine the effect of mixed-nut consumption on cardiovascular disease (CVD) risk factors in overweight and obese adults. In a randomized, parallel-arm, controlled trial, 48 participants consumed isocaloric (250 kcal) amounts of pretzels or mixed-nuts. Body weight (BW) (p = 0.024), BMI (p = 0.043), and insulin levels (p = 0.032) were significantly lower in the nut group compared to the pretzel group. Mixed-nut consumption also significantly reduced glucose (p = 0.04) and insulin (p = 0.032) levels after 4 and 8 weeks compared to baseline, respectively. Lactate dehydrogenase of the nut group was significantly lower than the pretzel group (p = 0.002). No significant differences were detected between groups for triglycerides, LDL-C, and HDL-C. However, pretzel consumption increased triglycerides (p = 0.048) from 4 weeks to 8 weeks. Moreover, LDL-C increased (p = 0.038) while HDL-C transiently decreased (p = 0.044) from baseline to 4 weeks. No significant lipid changes were detected within the nut group. Our results suggest that supplementing the diet with mixed-nuts could improve CVD risk factors by improving BW and glucose regulation in comparison to a common carbohydrate-rich snack without promoting the negative effects on lipids detected with pretzels.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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