The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study
Anton SD, Lee SA, Donahoo WT, McLaren C, Manini T, Leeuwenburgh C, Pahor M
Nutrients · 187 citations
How it was studied
- Design
- Controlled clinical trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- National Institutes of Health
- Government
- National Institute on Aging
- University or hospital
- Duke Claude D. Pepper Older Americans Independence Center, Duke Aging Center, Duke University
- University or hospital
- Claude D. Pepper Older Americans Independence Center
- Government
- NIA NIH HHS
- Grants
- Duke Claude D. Pepper Older Americans Independence Center, Duke Aging Center, Duke University (P30AG028740); National Institute on Aging (P30 AG028740); National Institutes of Health (P30AG028740)
Based on 5 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2019-06-30 · Nutrients · vol. 11 · issue 7 · p. 1500
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 233 citations · more than 99% of similar papers · 13.4× the field average
- Impact
- Top 10% most cited in its field
- References
- 29 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Diet and metabolism studies · Genetics, Aging, and Longevity in Model Organisms
- Keywords
- Overweight, Weight loss, Medicine, Waist, Adverse effect, Obesity, Quality of life (healthcare), Calorie restriction, Intermittent fasting, Gerontology, Intervention (counseling), Physical therapy, Internal medicine
- MeSH
- humans, weight loss, gait, treatment outcome, fasting, feasibility studies, pilot projects, feeding behavior, age factors, health status, recovery of function, energy intake, time factors, quality of life, aged, female, male, overweight, mobility limitation, sedentary behavior
7 authors
From US
- Stephen Douglas Anton · correspondingUniversity of Florida Health; University of Florida; Institute on Aging
- Stephanie A. LeeUniversity of Florida; Institute on Aging
- William Troy DonahooUniversity of Florida; Florida College
- Christian McLarenUniversity of Florida; Institute on Aging
- Todd Matthew ManiniUniversity of Florida; Institute on Aging
- Christiaan LeeuwenburghUniversity of Florida Health; University of Florida; Institute on Aging
Abstract
A growing body of evidence indicates that time restricted feeding (TRF), a popular form of intermittent fasting, can activate similar biological pathways as caloric restriction, the only intervention consistently found to extend healthy lifespan in a variety of species. Thus, TRF may have the potential to also improve function in older adults. Given the challenges many individuals have in following calorie restriction regimens over long-time periods, evaluation of alternative approaches that may produce weight loss and improve function in overweight, older adults is important. Ten overweight, sedentary older adults (≥65 years) at risk for, or with mobility impairments, defined by slow gait speed (p < 0.01). Since body composition was not measured in this study, it is unclear if the observed weight loss was due to loss of fat mass, muscle mass, or the combination of fat and muscle mass. There were no significant changes in other outcomes; however, there were clinically meaningful changes in walking speed and improvements in quality of life, with few reported adverse events. The findings of this pilot study suggest that time restricted feeding is an acceptable and feasible eating pattern for overweight, sedentary older adults to follow.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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