Study2020

What Dose of Caffeine to Use: Acute Effects of 3 Doses of Caffeine on Muscle Endurance and Strength

Grgic J, Sabol F, Venier S, Mikulic I, Bratkovic N, Schoenfeld BJ, Pickering C, Bishop DJ, Pedisic Z, Mikulic P

International journal of sports physiology and performance · 30 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Randomized controlled trial (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2019-09-30 · Int J Sports Physiol Perform · vol. 15 · issue 4 · pp. 470–477
Publisher
Human Kinetics
Cited
49 citations · more than 95% of similar papers · 4.7× the field average
Impact
Top 10% most cited in its field
References
32 works
Access
Free to read
Research areas
Coffee research and impacts · Smoking Behavior and Cessation · Tea Polyphenols and Effects
Keywords
Caffeine, Placebo, Medicine, Muscle strength, Internal medicine, Animal science, Endocrinology, Biology

10 authors

  • Jozo Grgić · corresponding
  • Filip Sabol
  • Sandro Venier
  • Ivan Mikulic
  • Nenad Bratković
  • Brad Jon Schoenfeld

Abstract

Purpose

To explore the effects of 3 doses of caffeine on muscle strength and muscle endurance.

Methods

Twenty-eight resistance-trained men completed the testing sessions under 5 conditions: no-placebo control, placebo control, and with caffeine doses of 2, 4, and 6 mg·kg-1. Muscle strength was assessed using the 1-repetition-maximum test; muscle endurance was assessed by having the participants perform a maximal number of repetitions with 60% 1-repetition maximum.

Results

In comparison with both control conditions, only a caffeine dose of 2 mg·kg-1 enhanced lower-body strength (d = 0.13-0.15). In comparison with the no-placebo control condition, caffeine doses of 4 and 6 mg·kg-1 enhanced upper-body strength (d = 0.07-0.09) with a significant linear trend for the effectiveness of different doses of caffeine (P = .020). Compared with both control conditions, all 3 caffeine doses enhanced lower-body muscle endurance (d = 0.46-0.68). For upper-body muscle endurance, this study did not find significant effects of caffeine.

Conclusions

This study revealed a linear trend between the dose of caffeine and its effects on upper-body strength. The study found no clear association between the dose of caffeine and the magnitude of its ergogenic effects on lower-body strength and muscle endurance. From a practical standpoint, the magnitude of caffeine's effects on strength is of questionable relevance. A low dose of caffeine (2 mg·kg-1)-for an 80-kg individual, the dose of caffeine in 1-2 cups of coffee-may produce substantial improvements in lower-body muscle endurance with the magnitude of the effect being similar to that attained using higher doses of caffeine.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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