The effect of egg consumption on cardiometabolic health outcomes: an umbrella review
Mah E, Chen CO, Liska DJ
Public health nutrition · 11 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Systematic review (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2019-10-10 · Public Health Nutr · vol. 23 · issue 5 · pp. 935–955
- Publisher
- Cambridge University Press
- Cited
- 20 citations · more than 90% of similar papers · 2.8× the field average
- References
- 54 works
- Access
- Free to read
- Research areas
- Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Antioxidant Activity and Oxidative Stress
- Keywords
- Meta-analysis, Medicine, Systematic review, Population, Disease, Environmental health, Cochrane Library, Cohort study, Type 2 Diabetes Mellitus, Gerontology, MEDLINE, Diabetes mellitus, Internal medicine, Endocrinology, Biology
- MeSH
- humans, cardiovascular diseases, heart diseases, metabolic diseases, diabetes mellitus, type 2, risk factors, eggs, female, male, heart failure, meta-analysis as topic, randomized controlled trials as topic, stroke, systematic reviews as topic
3 authors
- Eunice Mah
- C‐Y. Oliver Chen
- DeAnn J. Liska · corresponding
Abstract
Objective
This umbrella review provides an overview of the consistency and gaps in the evidence base on eggs and cardiometabolic health.
Design
PubMed, Web of Science, Cochrane Library, the Nutrition Evidence Systematic Review and Agency for Healthcare Research and Quality databases were screened for evidence-based reviews in English that assessed human studies on egg consumption and cardiometabolic outcomes.
Results
Seven systematic reviews and fifteen meta-analyses were identified, with eighteen of these published since 2015. Overall, the systematic reviews were of low quality, while meta-analyses were of moderate- to high-quality. No association of increased egg intake and risks of heart disease or stroke in the general population were found in the meta-analyses. Increased risk of heart failure was noted in two meta-analyses that analysed the same three cohort studies. Five recent meta-analyses reported no increased risk of type 2 diabetes mellitus (T2DM) in the general population, although increased risk in US-based populations only has been reported. Older (<2013) meta-analyses reported increased risks of cardiovascular disease (CVD) or heart disease in T2DM populations, and no recent evidence-based reviews were identified. Finally, only one meta-analysis reported intervention studies specifically on eggs and biomarkers (i.e. lipids), and the results contradicted those from observation studies.
Conclusions
Recent evidence-based reviews conclude that increased egg consumption is not associated with CVD risk in the general population. More research is needed on the positive associations between egg consumption and heart failure and T2DM risk, as well as CVD risk in diabetics, before firm conclusions can be made.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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