Egg intervention effect on linear growth no longer present after two years
Iannotti LL, Chapnick M, Nicholas J, Gallegos-Riofrio CA, Moreno P, Douglas K, Habif D, Cui Y, Stewart C, Lutter CK, Waters WF
Maternal & child nutrition · 26 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food diaries or recalls
Who paid for it
- Funding
- Possibly industry funded
- University or hospital
- Washington University in St. Louis
- Company
- Mathile Institute for the Advancement of Human Nutrition
- Company
- The Mathile Institute for the Advancement of Human Nutrition
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2019-12-17 · Matern Child Nutr · vol. 16 · issue 2 · p. e12925
- Publisher
- Wiley
- Cited
- 36 citations · more than 91% of similar papers · 3.0× the field average
- Impact
- Top 10% most cited in its field
- References
- 38 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Child Nutrition and Water Access · Obesity, Physical Activity, Diet · Child Nutrition and Feeding Issues
- Keywords
- Medicine, Anthropometry, Demography, Cohort, Cohort study, Randomized controlled trial, Linear growth, Pediatrics, Surgery, Internal medicine
- MeSH
- humans, growth disorders, body weight, anthropometry, body height, diet, longitudinal studies, follow-up studies, child development, eggs, child, preschool, ecuador, female, male
11 authors
From US, EC
- Lora Lynn Iannotti · correspondingWashington University in St. Louis; Saint Louis University
- Melissa ChapnickWashington University in St. Louis; Saint Louis University
- Jennifer Lynn NicholasWashington University in St. Louis; Mallinckrodt (United States)
- Carlos Andrés Gallegos-RiofríoWashington University in St. Louis; Saint Louis University; Universidad San Francisco de Quito
- Patricia I. MorenoUniversidad San Francisco de Quito
- Katherine DouglasWashington University in St. Louis; Mallinckrodt (United States)
Abstract
The Lulun Project, a randomized controlled trial conducted in 2015, found that one egg per day for 6 months during early complementary feeding reduced stunting by 47% and increased linear growth by 0.63 length-for-age Z (LAZ). This follow-up cohort study (Lulun Project II) aimed to test whether the growth effect remained in the egg intervention group compared with the control group after approximately 2 years. Mothers or caregivers from the Lulun Project were recontacted and recruited for this study. Enumerators collected data on socio-economic and demographic factors, 24-hr frequency of dietary intakes, morbidities, and anthropometric measures of height, weight, and head circumference using World Health Organization protocols. Statistical analyses followed the same analytical plan as Lulun Project, applying generalized linear models and regression modelling to test group differences in height-for-age z (HAZ) from LAZ at Lulun Project endline, and structural equation modelling for mediation. One hundred thirty-five mother-child dyads were included in Lulun II, with 11% losses to follow-up from endline Lulun Project. Growth faltering across all children was evident with HAZ -2.07 ± 0.91 and a stunting prevelance of 50%. Regression modelling showed no difference between egg and control groups for the HAZ outcome and other anthropometric outcomes, and significant declines in HAZ from endline Lulun Project in the egg intervention are compared with control groups. Current dietary egg intake, however, was associated with reduced growth faltering in HAZ from Lulun Project endline to Lulun Project II, independent of group assignment and through mediation, explaining 8.8% of the total effect. Findings suggest the need for a longer intervention period and ongoing nutrition support to young children during early childhood.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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